From: Hemodynamic and autonomic response to acute hemorrhage in streptozotocin-induced diabetic rats
 |  | baseline | 6% ETBV | 12% ETBV | 18% ETBV | 24% ETBV | 30% ETBV | 36% ETBV |
---|---|---|---|---|---|---|---|---|
 |  |  | loss | loss | loss | loss | loss | loss |
Hb (g/dL) | STZ | 12.9 ± 0.6 # | 12.8 ± 0.8 | 11.4 ± 0.3* | 10.1 ± 0.5* | 9.7 ± 0.6* | 9.3 ± 0.9* | 8.8 ± 0.8* |
 | Control | 14.1 ± 1.2 | 13.8 ± 0.7 | 11.6 ± 1.1* | 11.6 ± 1.0* | 10.2 ± 0.9* | 9.5 ± 0.6* | 8.9 ± 0.7* |
pH | STZ | 7.36 ± 0.03 # | 7.36 ± 0.01 | 7.37 ± 0.03 | 7.36 ± 0.03 | 7.37 ± 0.02 | 7.36 ± 0.01 | 7.35 ± 0.02* |
 | Control | 7.41 ± 0.04 | 7.42 ± 0.01 | 7.41 ± 0.02 | 7.42 ± 0.02 | 7.41 ± 0.02 | 7.41 ± 0.02 | 7.38 ± 0.01* |
PaCO2 (mmHg) | STZ | 35.7 ± 0.9 #. | 37.2 ± 2.4 | 34.2 ± 4.2 | 29.8 ± 1.5* | 28.4 ± 1.5* | 29.4 ± 1.7* | 26.7 ± 2.8* |
 | Control | 42.5 ± 4.6 | 39.0 ± 1.6 | 34.6 ± 2.6* | 33.6 ± 4.4* | 30.1 ± 4.4* | 26.8 ± 5.4* | 21.2 ± 3.9* |
HCO3- (mmol/L) | STZ | 21.6 ± 3.1# | 21.4 ± 2.2 | 19.7 ± 1.6 | 18.5 ± 0.9* | 17.5 ± 2.1* | 15.8 ± 2.8* | 13.6 ± 3.0* |
 | Control | 24.9 ± 2.1 | 25.1 ± 0.7 | 22.1 ± 1.3 | 22.0 ± 1.7 | 19.4 ± 1.6* | 16.5 ± 2.7* | 14.9 ± 1.3* |
BE (mEq/L) | STZ | -3.4 ± 1.5 # | -3.8 ± 2.2 | -3.7 ± 1.2 | -3.9 ± 2.3 | -2.8 ± 1.4 | -5.0 ± 1.9* | -7.2 ± 1.3* |
 | Control | 1.6 ± 1.5 | 1.1 ± 0.7 | -0.4 ± 1.3 | -1.2 ± 1.0* | -2.9 ± 1.3* | -4.3 ± 1.4* | -5.3 ± 1.3* |
RR (times/nin) | STZ | 84 ± 5 | 90 ± 5 | 100 ± 8 | 122 ± 7* | 137 ± 16* | 139 ± 20* | 144 ± 12* |
 | Control | 84 ± 4 | 86 ± 7 | 100 ± 6 | 119 ± 9* | 133 ± 18* | 141 ± 19* | 142 ± 15* |