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Table 4 Whole body and selected organ composition at the end of the study.

From: Glucagon-like peptide-1 and the exenatide analogue AC3174 improve cardiac function, cardiac remodeling, and survival in rats with chronic heart failure

  Sham Operated (N = 10) Vehicle Control (N = 12) GLPL (N = 11) GLPH (N = 12) 3174L (N = 13) 3174H (N = 7)
Body Wt (g) 511 ± 16 522 ± 17 523 ± 14 518 ± 12 493 ± 10 435 ± 15*
Baseline Body Wt (g) 257 ± 7 272 ± 8 270 ± 7 276 ± 10 258 ± 5 258 ± 5
Fat Mass (g) 58 ± 6 47 ± 6 45 ± 6 51 ± 9 33 ± 3* 26 ± 5*
Lean Mass (g) 35 ± 1 38 ± 1 37 ± 2 35 ± 2 38 ± 2 34 ± 1
Fluid Mass (g) 323 ± 12 343 ± 9 329 ± 14 331 ± 15 332 ± 11 305 ± 9*
LV (g) 1.07 ± 0.06* 1.36 ± 0.10 1.26 ± 0.05 1.13 ± 0.03* 1.13 ± 0.05* 1.06 ± 0.04*
RV (g) 0.22 ± 0.01* 0.28 ± 0.02 0.22 ± 0.01* 0.23 ± 0.01* 0.24 ± 0.01* 0.20 ± 0.02*
Lung (g) 1.53 ± 0.05* 2.45 ± 0.05 1.94 ± 0.35 1.66 ± 0.13* 1.48 ± 0.03* 1.51 ± 0.07*
LV Wt/Body Wt (%) 0.21 ± 0.01* 0.26 ± 0.01 0.24 ± 0.01 0.22 ± 0.01* 0.23 ± 0.01* 0.24 ± 0.01
RV Wt/Body Wt (%) 0.04 ± 0.002* 0.05 ± 0.01 0.04 ± 0.002* 0.04 ± 0.002* 0.05 ± 0.002 0.05 ± 0.002
Lung Wt/Body Wt (%) 0.30 ± 0.01* 0.48 ± 0.10 0.37 ± 0.07 0.32 ± 0.02* 0.30 ± 0.01* 0.33 ± 0.01*
Infarct Size (%) 0 ± 0 33 ± 4 30 ± 2 29 ± 2 31 ± 3 31 ± 6
  1. Mean ± SEM. *P < 0.05 versus vehicle-treated group. Wt, weight; LV, left ventricle; RV, right ventricle.