Skip to main content

Table 3 Multiple linear regression analysis of relationships between selected variables and estimated glomerular filtration rate or osteopontin

From: Plasma concentrations of osteopontin, but not thrombin-cleaved osteopontin, are associated with the presence and severity of nephropathy and coronary artery disease in patients with type 2 diabetes mellitus

Variable

β

SEM

P

Model A: Dependent variable eGFR

   Age

-0.889

0.127

< 0.001

   OPN

-11.967

3.823

0.002

Model B: Dependent variable OPN

   N-half OPN

-0.136

0.027

< 0.001

   hsCRP

0.103

0.017

< 0.001

   eGFR

-0.003

0.001

0.002

  1. In addition to the significant covariables shown in the table, Model A also included sex, cigarette smoking, systolic blood pressure (SBP), total cholesterol, triglyceride, lipoprotein (a), fasting glucose, use of angiotensin receptor blockers (ARBs) or angiotensin-converting enzyme inhibitors (ACEI), use of statins, log-transformed thrombin-cleaved osteopontin (N-half OPN), and log-transformed high-sensitivity C-reactive protein (hsCRP). Model B included sex, age, cigarette smoking, SBP, total cholesterol, triglyceride, lipoprotein (a), fasting glucose, use of ARBs or ACEI, and the use of statins.