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Table 2 Cardiovascular risk markers across tertiles of fibrinogen (g/L) for urban Indigenous Australian adults in the DRUID Study.

From: Fibrinogen and associated risk factors in a high-risk population: urban indigenous australians, the druid Study

 

Fibrinogen Tertiles

Females

Fibrinogen Tertiles

Males

 

Low*

(n = 201)

Mid*

(n = 210)

High*

(n = 217)

Low*

(n = 119)

Mid*

(n = 102)

High*

(n = 66)

Age (years)

35.0 ± 13.8

36.9 ± 15.3

40.1 ± 14.3

30.4 ± 13.2

35.3 ± 13.8

41.6 ± 13.6

BMI (kg/m2)

26.0 ± 7.1

28.1 ± 6.8

31.8 ± 7.9

25.6 ± 5.3

28.3 ± 5.5

29.3 ± 6.1

Waist (cm)

88.3 ± 17.2

91.8 ± 16.3

100.9 ± 16.4

90.6 ± 14.1

98.3 ± 13.6

102.1 ± 16.1

Systolic BP (mmHg)

113 ± 16

114 ± 16

118 + 16

117 ± 14

122 ± 14

126 ± 17

Diastolic BP

(mmHg)

71 ± 10

72 ± 10

75 ± 9

72 ± 11

75 ± 11

78 ± 10

Heart Rate (beats/min)

73 ± 11

74 ± 10

77 ± 12

70 ± 13

72 ± 12

77 ± 13

Diabetes (%)

12.2

19.0

31.0

8.2

13.5

32.8

Smoker (%)

48.4

41.5

42.3

39.8

43.8

45.9

Fibrinogen (g/L)

2.5 (2.4-2.6)

3.9 (3.88-3.96)

5.3 (5.2-5.4)

2.6 (2.5-2.8)

3.8 (3.76-3.89)

5.2 (5.1-5.4)

Total cholesterol (mmol/L)

4.8 (4.6 - 4.9)

4.9 (4.8 - 5.0)

4.9 (4.7 - 5.0)

4.8 (4.6 -5.0)

5.0 (4.8 - 5.2)

5.3 (5.1 - 5.6)

LDL Cholesterol (mmol/L)

2.8 (2.7 - 3.0)

2.9 (2.8 - 3.1)

3.0 (2.8 - 3.1)

2.9 (2.7 - 3.1)

3.0 (2.8 - 3.2)

3.3 (3.0 - 3.5)

HDL cholesterol (mmol/L)

1.2 (1.17 - 1.3)

1.15 (1.11- 1.2)

1.07(1.03- 1.1)

1.1 (1.0 - 1.2)

1.0 (0.9 - 1.0)

1.0 (0.9 - 1.0)

Triglycerides

(mmol/L)

1.2 (1.1 - 1.3)

1.4 (1.3 - 1.5)

1.5 (1.4 - 1.6)

1.4 (1.3 - 1.6)

1.9 (1.6 - 2.1)

2.1 (1.8 - 2.5)

HbA1c (%)

5.3 (5.2 - 5.4)

5.6 (5.4 - 5.7)

5.9 (5.8 - 6.1)

5.2 (5.1 - 5.3)

5.6 (5.4 - 5.8)

6.2 (5.8 - 6.5)

CRP (mg/L)

1.9(1.6 - 2.3)

3.2 (2.7 - 3.7)

8.0 (7.0 - 9.2)

1.2 (1.0 - 1.4)

2.5 (2.1 - 3.0)

7.0 (5.7 - 8.6)

Homocysteine (μmol/L)

8.8 (8.4-9.2)

8.8 (8.3-9.2)

9.3 (8.9-9.8)

9.6 (9.1-10.2)

11.7

(10.7-12.7)

11.4

(10.3-12.6)

ACR (mg/mmol)

0.8 (0.7 - 0.9)

1.0 (0.8 - 1.3)

1.2 (0.9 - 1.5)

0.5 (0.4 - 0.6)

0.6 (0.5 - 0.8)

1.6 (0.9 -2.7)

  1. Values are mean ± standard deviation or geometric mean (95% confidence interval) for continuous variables or percent for dichotomous parameters.
  2. BMI, body mass index; BP, blood pressure; CRP, c-reactive protein; ACR, urine albumin-creatinine ratio
  3. *Fibrinogen Tertiles: Low, 0.9-3.3; Mid, 3.4-4.4; High, 4.5-9.7 g/L