Table 1 Characteristics of the study participants by UCP2 genotype
UCP 2 G(-866)A polymorphism | AA+AG (N 198) | GG (N 185) | p |
|---|---|---|---|
Age (years) | 58.2 ± 7.5 | 58.0 ± 8.2 | 0.78 |
Males (%) | 52.5 | 47.5 | 0.22 |
BMI (kg/m2) | 30.5 ± 5.9 | 30.9 ± 5.8 | 0.46 |
Waist circumference (cm) | 100.9 ± 11.9 | 101.2 ± 12.0 | 0.82 |
Total cholesterol (mg/dl) | 197.9 ± 37.9 | 205.2 ± 43.9 | 0.09 |
HDL cholesterol (mg/dl) | 48.4 ± 11.7 | 48.6 ± 12.4 | 0.93 |
Triglycerides (mg/dl) | 149.8 ± 100.8 | 146.8 ± 91.8 | 0.75 |
HBA1c (%) | 7.4 ± 1.7 | 7.4 ± 1.7 | 0.78 |
Hs-CRP (mg/l) | 3.5 ± 4.7 | 4.8 ± 5.3 | 0.01 |
Proportion (%) with hs-CRP > 2 mg/L | 46.1 | 53.9 | 0.01 |
Current smokers (%) | 47.0 | 36.8 | 0.10 |
Metformin (%) | 25.6 | 29.7 | 0.48 |
Insulin secretagogues | 19.8 | 25.0 | 0.61 |
Insulin (%) | 54.5 | 45.3 | 0.34 |