Table 3 Parameters of cardiac assessment in IR(+) or IR(-), in subjects with normal glucose metabolism and in different degrees of glucose metabolism disturbances.

n

38 (18)

113 (54)

-

64 (31)

54 (26)

90 (43)

-

Diastolic function

Normal DF, n (%)

3 (8)

32 (28)

-

24 (38)

8 (15)

6 (7)

-

LVDD (any degree), n (%)

35 (92)

81 (72)

0.013*

40 (63)

46 (85)

84 (93)

0.001*

LVDD grade I, n (%)

23 (60%)

54 (48)

0.015*

29 (45)

34 (63)

49 (54)

0.001*

LVDD grade II, n (%)

12 (32)

27 (24)

0.017*

11 (17)

12 (22)

35 (39)

0.001*

IVS (mm)

11(11-13)

11 (10-13)

0.378

11 (10-13)

11 (10-13)

12 (11-14)

0.012*

Echocardiography

PLW (mm)

12 (9-12)

11 (10-13)

0.617

11 (9-13)

11 (10-13)

12 (10-14)

0.053

LVEDD (mm)

47 (43-49)

44 (40-48)

0.084

45 (41-48)

44 (40-49)

44 (39-48)

0.264

LVESD (mm)

30 (27-35)

30 (26-34)

0.984

31 (28-36)

29 (26-34)

28 (24-33)

0.037*

RWT

0.48 (0.44-0.58)

0.51 (0.43-0.62)

0.625

0.49 (0.40-0.58)

0.48 (0.44-0.59)

0.53 (0.46-0.64)

0.012*

LVM (g/m²)

87 (68-109)

84 (69-104)

0.900

83 (69-100)

84 (68-107)

90 (69-111)

0.430

LA- Index (ml/m²)

31 (25-38)

30 (24-36)

0.555

28 (24-32)

31 (25-37)

32 (27-38)

0.001*

EF biplan (%)

70 (63-73)

67 (62-71)

0.119

65 (61-70)

67 (63-73)

67 (62-73)

0.205

Smax (cm/s)

6.40 (5.70-7.10)

6.25 (5.50-7.15)

0.883

6.3 (5.6-7.3)

6.3 (5.4-7.0)

6.0 (5.3-7.1)

0.246

VE (cm/s)

70 (60-80)

60 (50-70)

0.155

60 (50-70)

60 (50-80)

70 (60-90)

0.012*

VA (cm/s)

80 (60-90)

70 (60-85)

0.115

70 (55-85)

70 (60-90)

80 (70-90)

<0.001*

VE/VA

0.8 (0.7-1.1)

0.9 (0.7-1.1)

0.566

0.9 (0.8-1.2)

0.9 (0.7-1.1)

0.8 (0.7-1.1)

0.218

E ' septal (cm/s)

5.7 (4.7-7.1)

6.1 (5.3-7.9)

0.099

6.5 (5.3-8.2)

6.2 (5.3-7.6)

5.6 (4.9-6.6)

0.001*

A ' (cm/s)

9.2 (8.0-10.2)

9.6 (8.4-10.4)

0.644

9.7 (8.7-10.4)

9.5 (8.6-10.4)

9.0 (7.810.2)

0.028*

E ' lateral (cm/s)

8.3 (6.5-9.1)

8.8 (7.0-10.6)

0.085

9.4 (7.3-10.9)

8.4 (6.6-10.2)

7.7 (6.5-9.2)

0.002*

Overage E'

7.3 (5.4-7.9)

7.5 (6.2-9.1)

0.061

7.9 (6.3-9.5)

7.3 (5.7-8.7)

6.8 (5.6-7.8)

<0.001*

E'/A' septal

0.6 (0.5-0.8)

0.7 (0.6-0.8)

0.102

0.7 (0.6-0.8)

0.7 (0.6-0.8)

0.7 (0.5-0.7)

0.087

E/E' septal

11.3 (9.6-15.1)

9.8 (7.7-12.7)

0.014*

8.9 (7.3-11.9)

10.2 (8.5-14.1)

12.2 (9.6-15.3)

<0.001*

Overage VE/E'

9.8 (8.3-11.5)

8.1 (6.6-11.0)

0.011*

7.6 (6.2-10.1)

8.8 (7.4-11.0)

10.5 (8.1-13.2)

<0.001*

PVsys (cm/s)

59 (50-66)

60 (51-67)

0.380

59 (50-65)

60 (51-68)

60 (55-68)

0.089

PVdia (cm/s)

46 (38-53)

43 (38-55)

0.839

44 (39-54)

43 (36-52)

46 (40-55)

0.468

PVsys/PVdia

1.2 (1.1-1.5)

1.3 (1.1-1.6)

0.346

1.3 (1.1-1.5)

1.4 (1.1-1.6)

1.4 (1.1-1.6)

0.325

PVa-max (cm/s)

31 (25-34)

31 (28-35)

0.240

31 (28-35)

31 (26-34)

32 (28-35)

0.382

GLS_Avg (-%)

19.3 (21.8-17.0)

19.5 (22.0-17.3)

0.812

20 (22-18)

19 (22-17)

19 (21-17)

0.363

Cardiac assessment

CAD, n (%)

23 (60)

62 (55)

0.339

26 (41)

37 (69)

57 (64)

0.003*

Hx. CABG

1 (3)

5 (5)

0.437

2 (3)

2 (4)

8 (9)

0.223

Hx. PTCA

14 (37)

46 (41)

0.412

14 (22)

28 (52)

43 (49)

0.001*

Hx. MI, n (%)

10 (26)

26 (23)

0.416

7 (11)

19 (35)

16 (18)

0.004*

NYHA (mean, SD)

2.0 (± 0.61)

1.9 (± 0.61)

0.337

1.8

1.8

2.0

0.249

NT-pro-BNP (pg/ml)

(143 ± 105-228)

131 (74-280)

0.916

116 (65-123)

126 (75-114)

152 (80-417)

0.283