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Table 4 Cox regression analysis of clinical and laboratory variables associated with diabetic foot presence

From: Adiponectin, resistin and IL-6 plasma levels in subjects with diabetic foot and possible correlations with clinical variables and cardiovascular co-morbidity

  Univariate analysis Multivariate analysis
  Regression
coefficient
Hazard ratio
(95% CI)
P value Regression
coefficient
Hazard ratio
(95% CI)
P value
Age 0.69 2.32 (1.78-5.19) 0.021 0.49 2.12 (182-4.48) 0.031
Diabetes duration (y) 1.56 7.26 (3.80-13.87) <0.001 1.21 5.67 (2.70-8.34) <0.001
Hypercholesterolemia 0.59 1.55 (1.16-2.64) 0.21 0.44 0.87 (0.166-1.62) 0.42
Hypertension (n/%) 0.32 0.78 (1.70-4.34) 0.33 0.39 0.67 (0.30-1.12) 0.71
Obesity (n/%) 0.32 0.86 (0.31-1.23) 0.23 0.29 0.77 (0.42-0.98) 0.56
Chronic renal failure (n/%) 0.11 0.89 (0.53-1.31) 0.35 0.11 0.59 (0.21-0.89) 0.71
Mycroalbuminuria (n/%) 0.41 1.87 (1.32-3.51) 0.018 0.41 1.55 (1.11-2.99) 0.032
Retinopathty (n/%) 0.33 2.31 (1.78-4.78) 0.012 0.33 1.99 (1.45-3.24) 0.021
PAD (n/%) 0.61 3.5 (2.7-4.1) <0.005 0.59 2.9 (2.1-3.8) <0.005
CAD (n/%) 0.54 1.6 (1.4--2.7) 0.033 0.54 0.89 (0.5-1.1) 0.56
TIA/Stroke (n/%) 0.42 1.4 (1.21-2.09) 0.041 0.42 0.78 (0.33-0.91) 0.44
IL-6 1.12 4.8 (3.1-5.5) <0.005 0.98 3.6 (2.8-4.1) <0.005
Resistin 0.49 2.1 (1.4-3.9) 0.041 0.43 1.78 (1.4-2.9) 0.031
Adyponectin -0.29 -3.4 (-1.9-3.6) <0.001 -0.29 -2.9 (-1.5-3.4) <0.001