Skip to main content

Table 4 Cox regression analysis of clinical and laboratory variables associated with diabetic foot presence

From: Adiponectin, resistin and IL-6 plasma levels in subjects with diabetic foot and possible correlations with clinical variables and cardiovascular co-morbidity

 

Univariate analysis

Multivariate analysis

 

Regression

coefficient

Hazard ratio

(95% CI)

P value

Regression

coefficient

Hazard ratio

(95% CI)

P value

Age

0.69

2.32 (1.78-5.19)

0.021

0.49

2.12 (182-4.48)

0.031

Diabetes duration (y)

1.56

7.26 (3.80-13.87)

<0.001

1.21

5.67 (2.70-8.34)

<0.001

Hypercholesterolemia

0.59

1.55 (1.16-2.64)

0.21

0.44

0.87 (0.166-1.62)

0.42

Hypertension (n/%)

0.32

0.78 (1.70-4.34)

0.33

0.39

0.67 (0.30-1.12)

0.71

Obesity (n/%)

0.32

0.86 (0.31-1.23)

0.23

0.29

0.77 (0.42-0.98)

0.56

Chronic renal failure (n/%)

0.11

0.89 (0.53-1.31)

0.35

0.11

0.59 (0.21-0.89)

0.71

Mycroalbuminuria (n/%)

0.41

1.87 (1.32-3.51)

0.018

0.41

1.55 (1.11-2.99)

0.032

Retinopathty (n/%)

0.33

2.31 (1.78-4.78)

0.012

0.33

1.99 (1.45-3.24)

0.021

PAD (n/%)

0.61

3.5 (2.7-4.1)

<0.005

0.59

2.9 (2.1-3.8)

<0.005

CAD (n/%)

0.54

1.6 (1.4--2.7)

0.033

0.54

0.89 (0.5-1.1)

0.56

TIA/Stroke (n/%)

0.42

1.4 (1.21-2.09)

0.041

0.42

0.78 (0.33-0.91)

0.44

IL-6

1.12

4.8 (3.1-5.5)

<0.005

0.98

3.6 (2.8-4.1)

<0.005

Resistin

0.49

2.1 (1.4-3.9)

0.041

0.43

1.78 (1.4-2.9)

0.031

Adyponectin

-0.29

-3.4 (-1.9-3.6)

<0.001

-0.29

-2.9 (-1.5-3.4)

<0.001