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Figure 4 | Cardiovascular Diabetology

Figure 4

From: Sirtuin1-p53, forkhead box O3a, p38 and post-infarct cardiac remodeling in the spontaneously diabetic Goto-Kakizaki rat

Figure 4

Increased interstitial fibrosis in the remote area of diabetic GK rat myocardium 12 weeks after MI. Panel (A) shows picrosirius--red stained photomicrograph images (×100 original magnitude), from the remote area of the left ventricle in sham- and MI operated GK and Wistar rats. In panel B, results from collagen volume fraction measurements show increased interstitial fibrosis in the remote area in GK rats with MI. Data is presented as means ± SEM; * indicates P < 0.05 vs. W (sham-operated Wistar, † indicates P < 0.05 vs. W+MI.

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Cardiovascular Diabetology

ISSN: 1475-2840