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Table 4 Concentrations of CRP according to the HNF1A carrier status among participants with diabetes

From: Assessing the association of the HNF1A G319S variant with C-reactive protein in Aboriginal Canadians: a population-based epidemiological study

  Beta SE CRP [95% CI] (mg/L)* p
    G/G319 S/G + S/S319  
Model 1† -0.2162 0.1847 4.79 (3.33-6.88) 3.86 (2.69-5.54) 0.24
Model 2‡ -0.3514 0.2354 5.05 (3.18-8.01) 3.52 (2.22-5.58) 0.13
Model 3§ -0.2971 0.2286 4.96 (3.17-7.77) 3.69 (2.36-5.77) 0.20
Model 4 -0.0109 0.1786 4.44 (3.13-6.30) 4.39 (3.09-6.23) 0.95
  1. *Least square mean CRP values are back-transformed after using log-transformed CRP to calculate p-values. Group sample sizes of 77 (G/G319) and 47 (S/G + S/S319) have 99.9% power to detect a difference between mean CRP concentrations ± standard deviations of 4.79 ± 1.03 (G/G319) and 3.86 ± 0.93 (S/G + S/S319) at a significance level of 0.05. †Model 1: unadjusted ‡Model 2: adjusted for age, sex, log 2-h post-load glucose §Model 3: adjusted for model 2 variable and waist circumference Model 4: adjusted for model 3 variables and log serum amyloid A