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Table 1 Characteristics of participants according to the HNF1AG319S carrier status

From: Assessing the association of the HNF1A G319S variant with C-reactive protein in Aboriginal Canadians: a population-based epidemiological study

Characteristic G/G319 S/G + S/S319 p
n (%) 554 (78.6) 151 (21.4)  
Age (years)* 30.0 ± 15.9 30.6 ± 15.4 0.70
Sex, male† 220 (39.7) 76 (50.3) 0.02
BMI (kg/m2)* 26.6 ± 5.90 27.0 ± 5.22 0.52
Waist circumference (cm)* 97.6 ± 14.7 99.1 ± 13.2 0.24
Hypertension, yes†‡ 119 (21.5) 30 (19.9) 0.67
HDL cholesterol (mmol/l)* 1.25 ± 0.28 1.23 ± 0.27 0.46
LDL cholesterol (mmol/l)* 2.59 ± 0.74 2.56 ± 0.79 0.75
Triglyceride (mmol/l) § 1.25 (0.88-1.71) 1.27 (0.97-1.87) 0.06
Fasting glucose (mmol/l) § 5.4 (5.1-5.9) 5.6 (5.0-7.6) < 0.0001
2-hour postload glucose (mmol/l) § 5.7 (4.4-7.2) 6.0 (4.8-9.8) 0.002
HOMA-insulin resistance§ 3.61 (2.38-6.27) 3.96 (2.16-6.87) 0.44
HOMA-beta§ 144.4 (98.3-204.5) 110.3 (67.8-180.5) 0.0004
C-reactive protein (mg/l) § 2.17 (0.63-5.73) 1.85 (0.57-5.05) 0.29
Serum amyloid A (mg/l) § 7.71 (4.73-12.98) 7.18 (5.03-11.39) 0.48
  1. Abbreviation: BMI, body mass index; HDL high-density lipoprotein; LDL low-density lipoprotein; HOMA, homoeostasis model assessment. N of subjects for each characteristic varying slightly due to occasional missing values. *Mean ± standard deviation and Welch's t test performed. †n (%) and Chi-Square test performed. ‡Hypertension is defined as a systolic blood pressure ≥130 mmHg or diastolic blood pressure of ≥85 mmHg or receiving antihypertensive medication therapy. §Medians (25th-75th percentile) and Welch's t test performed on log transformation.