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Table 1 Comparisons of anthropometric and metabolic characteristics among 3 genotypes at rs2283228

From: KCNQ1 gene polymorphisms are associated with lipid parameters in a Chinese Han population

  Genotype P
rs2283228 AA AC CC  
Numbers 156 191 51  
Sex, male (n/%) 77/49.3 90/47.1 27/52.9 0.746
Age, years 51.67 ± 5.50 51.28 ± 5.47 52.53 ± 5.72 0.836
Hypertension, n/% 83/53.2 121/63.3 31/60.7 0.155
Type 2 diabetes mellitus, n/% 21/13.5 29/15.2 7/13.7 0.894
Family history of CAD, n/% 64/41.0 73/38.2 17/33.3 0.609
Smokers, n/% 53/33.9 69/36.1 17/33.3 0.887
BMI, kg/m2 24.29 ± 3.46 24.93 ± 3.81 24.33 ± 3.00 0.227
FBS, mmol/L 5.73 ± 1.72 5.57 ± 0.98 5.87 ± 1.86 0.408
Insulin, mU/L 14.31 ± 11.87 13.16 ± 9.84 17.32 ± 13.08 0.351
HOMA-IR 3.64 ± 0.59 3.56 ± 0.57 4.36 ± 0.83 0.138
TC, mmol/L 4.65 ± 0.93 4.39 ± 0.86 4.63 ± 0.78 0.116
TG, mmol/L 1.53 ± 0.76 1.50 ± 0.80 2.03 ± 0.84 0.007
LDL-C, mmol/L 2.82 ± 0.80 2.71 ± 0.74 2.74 ± 0.84 0.604
HDL-C, mmol/L 1.21 ± 0.30 1.14 ± 0.25 1.07 ± 0.22 0.052
Apo A1, g/L 1.15 ± 0.18 1.11 ± 0.19 1.08 ± 0.16 0.055
Apo B, g/L 0.87 ± 0.25 0.86 ± 0.25 0.97 ± 0.23 0.115
  1. Data are mean ± SD, or number (%), as appropriate.
  2. P is the significance level of comparison of clinical and plasma parameters among 3 groups by one-way ANOVA or chi-square test.
  3. Apo A1, apolipoprotein A1; Apo B, apolipoprotein B; BMI, body mass index; CAD, coronary artery disease; FBS, fasting blood sugar; HDL-C, high-density lipoprotein cholesterol; HOMA-IR, homeostasis model assessment-insulin resistance; LDL-C, low-density lipoprotein cholesterol; SNPs, single nucleotide polymorphisms; TC, total cholesterol; TG, triglyceride.