Table 3 Metabolic parameters for clamp studies
From: Hyperinsulinemia improves ischemic LV function in insulin resistant subjects
Glucose (mg/dl) | Insulin Sensitive | Insulin Resistant | p | C-peptide (pmol/l) | Insulin Sensitive | Insulin Resistant | p |
|---|---|---|---|---|---|---|---|
Baseline | 88 (14) | 104 (27) | 0.07 | Baseline | 683 (291) | 1251 (352) | 0.001 |
Steady state | 86 (11) | 106 (13) | 0.0004 | Steady state | 493 (219) | 1124 (361) | 0.0002 |
Peak Stress | 88 (11) | 106 (11) | 0.0004 | Peak Stress | 804 (334) | 1465 (524) | 0.004 |
Recovery | 93 (18) | 106 (20) | ns | Recovery | 836 (363) | 1374 (646) | 0.04 |
Insulin (pmol/l) | Â | Â | Â | FFA (nmol/l) | Â | Â | Â |
Baseline | 38.9 (18.7) | 102 (27.6) | < 0.0001 | Baseline | 374 (153) | 548 (299) | ns |
Steady state | 447 (78.6) | 624 (150) | 0.004 | Steady state | 49.2 (51.3) | 114 (72) | 0.04 |
Peak Stress | 386 (82.9) | 523 (198) | 0.06 | Peak Stress | 365 (160) | 374 (113) | ns |
Recovery | 90.1 (45.3) | 174 (117) | 0.05 | Recovery | 83.9 (79.1) | 197 (52.1) | 0.002 |