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Table 1 Effect of age and the treatment of Rosiglitazone on body weight, average arterial pressure, blood glucose, and triglycerides.

From: Rosiglitazone reverses endothelial dysfunction but not remodeling of femoral artery in Zucker diabetic fatty rats

 

11 weeks

19 weeks

19 weeks

Determination

Lean

ZDF

Lean

ZDF

Veihcle

Rosi

Number of Animals

6

7

6

6

6

6

Age of Animal (weeks)

11.8 ± 1.2

11.3 ± 0.9

19.7 ± 1.5

19.2 ± 1.1

19.6 ± 1.5

19.3 ± 1.2

Average Pressure (mmHg)

69.2 ± 8.9

71.7 ± 9.3

72.2 ± 9.7

74.8 ± 11.6

71.9 ± 10.3

73.9 ± 11.8

Body Weight (grams)

339 ± 38

369 ± 35

382 ± 35

401 ± 37*

403 ± 29*

423 ± 33*

Glucose (mg/dl)

112.8 ± 16.1

457.8 ± 35.9*

116.3 ± 15.0

431.4 ± 30.3*

472.0 ± 46.0*

445.6 ± 48.8*

Triglyceride (mg/dl)

108.3 ± 11.9

583.4 ± 49.5*

121.8 ± 16.5

602.6 ± 59.7*

609.1 ± 79.7*

613.1 ± 46.5*

  1. Notes: Lean: Zucker lean rats. ZDF: Zucker diabetic fatty rats. Rosi: rosiglitazone treated. * p < 0.05 compared with lean rats.