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Table 1 Patients characteristics by cardiovascular diseases at baseline (before and after propensity score 1:1 matching)

From: Pre-existing cardiovascular diseases and glycemic control in patients with type 2 diabetes mellitus in Europe: a matched cohort study

 

Before Matching

After Matching

Variables

Mean (S.D.)

P-value

Mean (S.D.)

P-value

 

With CVD (N = 406)

Without CVD (N = 1536)

 

With CVD (N = 394)

Without CVD (N = 394)

 

SU added at index

80.8%

73.6%

0.003

-

-

-

Glitazones added at index

19.2%

26.4%

 

-

-

-

Demographics

      

Age (years)

64.3 (9.2)

59.5 (10.5)

< 0.0001

64.0 (9.0)

63.9 (10.1)

0.96

Male

65.5%

51.3%

< 0.0001

65.0%

70.3%

0.11

Caucasian

98.0%

96.7%

0.17

98.0%

98.4%

0.68

Duration of diabetes (years)

6.1 (5.2)

5.6 (4.8)

0.09

6.0 (5.0)

6.1 (5.0)

0.99

Never used alcohol

27.6%

30.4%

0.29

27.9%

26.1%

0.57

Physical Activity

      

   No regular activity

39.1%

34.6%

0.11

37.6%

39.5%

0.58

   < 3 times/week

39.1%

39.7%

0.83

41.0%

36.5%

0.12

   ≥ 3 times/week

21.9%

25.7%

0.12

21.4%

24.0%

0.34

Country

      

   Spain

15.8%

28.1%

< 0.0001

16.2%

15.0%

0.62

   France

6.9%

8.1%

0.43

7.1%

6.9%

0.89

   UK

26.6%

16.9%

< 0.0001

26.7%

26.4%

0.94

   Norway

3.0%

3.4%

0.67

3.1%

4.8%

0.20

   Finland

7.4%

10.7%

0.049

7.6%

10.2%

0.21

   Germany

17.7%

21.4%

0.10

18.3%

19.8%

0.59

   Poland

22.7%

11.5%

< 0.0001

21.1%

17.0%

0.15

Baseline Clinical Information

      

HbA1c (%)

8.1 (1.3)

8.0 (1.4)

0.69

8.06 (1.26)

8.05 (1.39)

0.96

With HbA1c < 6.5%

5.2%

8.3%

0.037

5.1%

7.6%

0.14

Body mass index (kg/m2)

31.7 (8.2)

31.9 (6.2)

0.60

31.7 (6.6)

31.7 (6.7)

0.94

Physician specialty

      

   Endocrinologists/Diabetologists

40.6%

40.6%

0.99

40.6%

41.1%

0.89

   General practitioners/Internists

59.4%

59.4%

 

59.4%

58.9%

 

Duration of metformin use (years)

3.0 (2.9)

2.8 (2.5)

0.15

2.9 (2.7)

2.8 (2.5)

0.60

  1. Note: CVD: cardiovascular diseases; S.D.: standard deviation.