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Table 3 The correlation between PPARγ polymorphism and a severity of atherosclerosis and restenosis in CAD with T2DM group

From: PPARγ gene C161T substitution alters lipid profile in Chinese patients with coronary artery disease and type 2 diabetes mellitus

 

PPARγ genotypes

Groups

CC

CT

TT#

CT+TT*

Modest stenosis<75%

85 (57.4%)

58 (39.2%)

5(3.4%)

63(42.6%)

Severe stenosis>75%

109(70.3%)

39(25.2%)

7(4.5%)

46(29.7%)

Total (303)

194(64%)

97(32%)

12(4%)

109(36%)

  1. Number of patients is presented in each subgroup with a row percentage in the bracket. #χ2 = 6.607, P = 0.010, for comparisons among CC, CT and TT genotypes. *χ2 = 5.462, P = 0.019 for comparison between CC genotype and "T" allele carriers (CT+TT genotype). Taking CC genotype as the risk allele, the corresponding odds ratio with 95% confidential interval is 1.22 (1.03-1.45).
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Cardiovascular Diabetology

ISSN: 1475-2840