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Table 3 The correlation between PPARγ polymorphism and a severity of atherosclerosis and restenosis in CAD with T2DM group

From: PPARγ gene C161T substitution alters lipid profile in Chinese patients with coronary artery disease and type 2 diabetes mellitus

  PPARγ genotypes
Groups CC CT TT# CT+TT*
Modest stenosis<75% 85 (57.4%) 58 (39.2%) 5(3.4%) 63(42.6%)
Severe stenosis>75% 109(70.3%) 39(25.2%) 7(4.5%) 46(29.7%)
Total (303) 194(64%) 97(32%) 12(4%) 109(36%)
  1. Number of patients is presented in each subgroup with a row percentage in the bracket. #χ2 = 6.607, P = 0.010, for comparisons among CC, CT and TT genotypes. *χ2 = 5.462, P = 0.019 for comparison between CC genotype and "T" allele carriers (CT+TT genotype). Taking CC genotype as the risk allele, the corresponding odds ratio with 95% confidential interval is 1.22 (1.03-1.45).