Table 4 Data in Control Subjects
Exercise Parameters | Baseline | 6 weeks | 24 weeks |
|---|---|---|---|
Exercise duration (min) | 4.3 ± 1.1 | 5.5 ± 3.2 | 6.6 ± 2.1 |
Maximal oxygen consumption (mL/kg/min) | 10.9 ± 1.0 | 11.8 ± 2.0 | 11.9 ± 1.3 |
Oxygen consumption (isotime) (mL/kg/min) | 9.1 ± 0.3 | 9.0 ± 0.2 | 9.8 ± 0.5 |
Resting heart rate (bpm) | 75 ± 16 | 76 ± 10 | 70 ± 19 |
Maximum heart rate (bpm) | 112 ± 16 | 107 ± 16 | 105 ± 13 |
Resting systolic blood pressure (mmHg) | 157 ± 14 | 156 ± 23 | 136 ± 5 |
Resting diastolic blood pressure (mmHg) | 83 ± 20 | 77 ± 12 | 77 ± 8 |
Maximum systolic blood pressure (mmHg) | 207 ± 28 | 188 ± 47 | 184 ± 22 |
Maximum RPP# | 23219 ± 6046 | 20939 ± 7809 | 19373 ± 4215 |
Mean ± SD # rate pressure product = heart rate × systolic blood pressure | |||
Renal Function Parameters | Baseline | 6 weeks | 24 weeks |
Serum creatinine (mg/dL) | 2.3 ± 0.1 | 2.1 ± 0.2 | 2.1 ± 0.4 |
Serum urea nitrogen (mg/dL) | 45 ± 11 | 48 ± 12 | 50 ± 18 |
Creatinine clearance (mL/min) | 66 ± 19 | 54 ± 22 | 64 ± 10 |
Urea clearance (mL/min) | 28 ± 0.2 | 18 ± 5.7 | 19 ± 0.5 |
Glomerular filtration rate (mL/min)# | 47 ± 9.5 | 36 ± 14 | 41 ± 5.3 |
Urine albumin/creatinine (mg/g) | 156 ± 148 | 162 ± 173 | 221 ± 304 |
Urine protein/creatinine (mg/g) | 347 ± 178 | 305 ± 186 | 387 ± 374 |
Urine protein excretion (mg/24 h) | 542 ± 258 | 383 ± 256 | 490 ± 237 |
   # (Creatinine clearance + urea clearance)/2 | |||
Biochemical Parameters | Baseline | 6 weeks | 24 weeks |
Hemoglobin (g/dL) | 11.8 ± 1.9 | 12.0 ± 1.8 | 11.9 ± 1.3 |
Total cholesterol (mg/dL) | 152 ± 38 | 160 ± 53 | 146 ± 31 |
Low density cholesterol (mg/dL) | 75 ± 24 | 80 ± 41 | 69 ± 22 |
High density cholesterol (mL/min) | 33 ± 6 | 31 ± 3 | 31 ± 4 |
Triglycerides (mg/dL) | 223 ± 92 | 245 ± 44 | 225 ± 104 |
Glycated hemoglobin (%) | 8.2 ± 1.7 | 8.7 ± 2.6 | 8.1 ± 3.7 |
C-reactive protein (mg/dL) | 1.7 ± 2.4 | 0.73 ± 0.32 | 1.17 ± 0.71 |
Body Composition Parameters | Baseline | 6 weeks | 24 weeks |
Calorie intake (kcal/day) | 1869 ± 13 | 2165 ± 658 | 2192 ± 537 |
Body weight (kg) | 140 ± 15 | 139 ± 15 | 136 ± 20 |
Fat weight (%) | 50 ± 5 | 53 ± 3 | 50 ± 5 |
Lean weight (%) | 50 ± 5 | 47 ± 3 | 50 ± 5 |