Exercise Parameters | Baseline | 6 weeks | 24 weeks |
---|---|---|---|
Exercise duration (min) | 6.6 ± 2.2 | 11.3 ± 2.4 | 10.2 ± 2.8 |
Maximal oxygen consumption (mL/kg/min) | 14.9 ± 1.1 | 13.8 ± 3.9 | 15.6 ± 2.4 |
Oxygen consumption (isotime) (mL/kg/min) | 11.9 ± 1.7 | 10.0 ± 0.7 | 9.8 ± 1.4 |
Resting heart rate (bpm) | 80 ± 16 | 82 ± 22 | 81 ± 21 |
Maximum heart rate (bpm) | 116 ± 16 | 121 ± 14 | 118 ± 17 |
Resting systolic blood pressure (mmHg) | 130 ± 28 | 132 ± 13 | 113 ± 16 |
Resting diastolic blood pressure (mmHg) | 71 ± 20 | 71 ± 11 | 65 ± 10 |
Maximum systolic blood pressure (mmHg) | 182 ± 16 | 188 ± 24 | 165 ± 21 |
Maximum RPP# | 21094 ± 3475 | 22616 ± 1983 | 19206 ± 1402 |
Mean ± SD # rate pressure product = heart rate × systolic blood pressure | |||
Renal Function Parameters | Baseline | 6 weeks | 24 weeks |
Serum creatinine (mg/dL) | 2.9 ± 1.5 | 2.7 ± 1.3 | 2.8 ± 1.2 |
Serum urea nitrogen (mg/dL) | 64 ± 40 | 58 ± 48 | 57 ± 34 |
Creatinine clearance (mL/min) | 64 ± 54 | 62 ± 40 | 51 ± 26 |
Urea clearance (mL/min) | 24 ± 20 | 28 ± 22 | 26 ± 19 |
Glomerular filtration rate (mL/min)# | 44 ± 36 | 45 ± 31 | 39 ± 22 |
Urine albumin/creatinine (mg/g) | 327 ± 385 | 242 ± 260 | 305 ± 456 |
Urine protein/creatinine (mg/g) | 565 ± 600 | 419 ± 417 | 493 ± 544 |
Urine protein excretion (mg/24 h) | 1020 ± 1081 | 891 ± 831 | 821 ± 1010 |
   # (Creatinine clearance + urea clearance)/2 | |||
Biochemical Parameters | Baseline | 6 weeks | 24 weeks |
Hemoglobin (g/dL) | 12.7 ± 2.1 | 12.7 ± 2.2 | 12.5 ± 1.8 |
Total cholesterol (mg/dL) | 125 ± 25 | 116 ± 17 | 128 ± 25 |
Low density cholesterol (mg/dL) | 59 ± 17 | 51 ± 16 | 54 ± 11 |
High density cholesterol (mL/min) | 38 ± 6 | 37 ± 5 | 39 ± 7 |
Triglycerides (mg/dL) | 137 ± 45 | 144 ± 60 | 179 ± 89 |
Glycated hemoglobin (%) | 7.4 ± 1.1 | 7.5 ± 1.2 | 8.3 ± 2.4 |
C-reactive protein (mg/dL) | 0.55 ± 0.72 | 0.72 ± 0.99 | 0.89 ± 0.92 |
Nutrition/Body Composition Parameters | Baseline | 6 weeks | 24 weeks |
Calorie intake (kcal/day) | 1878 ± 563 | 2011 ± 396 | 1939 ± 656 |
Body weight (kg) | 116 ± 27 | 116 ± 26 | 115 ± 23 |
Fat weight (%) | 40 ± 3 | 40 ± 3 | 40 ± 4 |
Lean weight (%) | 60 ± 3 | 60 ± 3 | 60 ± 4 |