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Table 1 Hazard ratios for cardiovascular and overall mortality at 5 years follow-up in accordance to baseline values of YKL-40 in a representative group of the general population without known cardiovascular disease or diabetes

From: YKL-40 - an emerging biomarker in cardiovascular disease and diabetes

  

HR (95% CI)

  

Cardiovascular mortality

P value

Overall mortality

p value

Unadjusted

2.16 (1.67-2.80)

< 0.0001

2.29 (1.53-3.44)

< 0.0001

Age- and sex-adjusted

1.75 (1.29-2.37)

< 0.0001

1.99 (1.26-3.16)

0.003

Mutivariable model

1.57 (1.16-2.14)

0.004

1.57 (1.00-2.46)

0.049

  1. 1 SD increase in ln variable.
  2. N = 482, cardiovascular mortality events = 22, overall mortality events = 45.
  3. * Variables: hypertension, total cholesterol, smoking, hsCRP, NT-proBNP and UACR.
  4. Abbreviations: CI, confidence interval; HR, hazard ratio; hsCRP, high sensitive C-reactive protein; NT-proBNP, N-amino terminal fragment of the prohormone brain natriuretic peptide; UACR, urinary albumin/creatinine ratio.