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Table 3 Age- and sex- or multivariate-adjusted odds ratios for cardiovascular diseases according to serum resistin quintiles.

From: Diabetes and hypertension markedly increased the risk of ischemic stroke associated with high serum resistin concentration in a general Japanese population: the Hisayama Study

  Serum resistin level (ng/ml)
1.5-6.7 6.8-8.7 8.8-11.5 11.6-16.2 16.3-90.2 P value for trend
No cardiovascular disease, n 628 610 604 595 589  
Cardiovascular disease, n 20 23 37 41 54  
   Model 1-adjusted OR (95% CI) 1
(referent)
0.95
(0.51-1.76)
1.55
(0.88-2.74)
1.51
(0.86-2.64)
1.64
(0.95-2.84)
0.02
   Model 2-adjusted OR (95% CI) 1
(referent)
0.88
(0.47-1.66)
1.56
(0.88-2.77)
1.39
(0.79-2.45)
1.52
(0.87-2.66)
0.04
   Model 3-adjusted OR (95% CI) 1
(referent)
0.87
(0.46-1.63)
1.53
(0.86-2.72)
1.36
(0.77-2.41)
1.47
(0.84-2.58)
0.06
Ischemic stroke, n 4 11 17 25 33  
   Model 1-adjusted OR (95% CI) 1
(referent)
2.21
(0.70-7.05)
3.54
(1.17-10.67)
4.48
(1.53-13.09)
4.70
(1.62-13.61)
< 0.001
   Model 2-adjusted OR (95% CI) 1
(referent)
1.94
(0.60-6.23)
3.36
(1.11-10.22)
3.87
(1.31-11.39)
3.97
(1.36-11.61)
0.002
   Model 3-adjusted OR (95% CI) 1
(referent)
1.84
(0.57-5.96)
3.26
(1.07-9.92)
3.66
(1.24-10.79)
3.59
(1.22-10.55)
0.006
Hemorrhagic stroke, n 9 7 9 7 11  
   Model 1-adjusted OR (95% CI) 1
(referent)
0.70
(0.26-1.92)
0.93
(0.36-2.37)
0.66
(0.24-1.80)
0.89
(0.36-2.23)
0.83
   Model 2-adjusted OR (95% CI) 1
(referent)
0.70
(0.26-1.92)
1.02
(0.39-2.64)
0.70
(0.25-1.93)
0.98
(0.38-2.50)
0.99
   Model 3-adjusted OR (95% CI) 1
(referent)
0.69
(0.25-1.90)
1.00
(0.39-2.60)
0.69
(0.25-1.90)
0.96
(0.37-2.46)
0.97
Coronary heart disease, n 9 6 12 11 17  
   Model 1-adjusted OR (95% CI) 1
(referent)
0.55
(0.19-1.57)
1.13
(0.47-2.73)
0.88
(0.36-2.18)
1.11
(0.48-2.59)
0.48
   Model 2-adjusted OR (95% CI) 1
(referent)
0.48
(0.16-1.41)
1.20
(0.49-2.95)
0.79
(0.31-1.99)
1.05
(0.44-2.50)
0.53
   Model 3-adjusted OR (95% CI) 1
(referent)
0.49
(0.17-1.42)
1.21
(0.49-2.97)
0.80
(0.32-2.02)
1.09
(0.45-2.59)
0.49
  1. OR: odds ratio; CI: confidence interval. Model 1: adjustment was made for age and sex; Model 2: adjustment was made for age, sex, body mass index, diabetes, total cholesterol, HDL cholesterol, systolic blood pressure, electrocardiographic abnormalities, current drinking, current smoking, and regular exercise; Model 3: adjustment was made for the variables used in Model 2 and for high sensitivity C-reactive protein.