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Table 3 Age- and sex- or multivariate-adjusted odds ratios for cardiovascular diseases according to serum resistin quintiles.

From: Diabetes and hypertension markedly increased the risk of ischemic stroke associated with high serum resistin concentration in a general Japanese population: the Hisayama Study

 

Serum resistin level (ng/ml)

1.5-6.7

6.8-8.7

8.8-11.5

11.6-16.2

16.3-90.2

P value for trend

No cardiovascular disease, n

628

610

604

595

589

 

Cardiovascular disease, n

20

23

37

41

54

 

   Model 1-adjusted OR (95% CI)

1

(referent)

0.95

(0.51-1.76)

1.55

(0.88-2.74)

1.51

(0.86-2.64)

1.64

(0.95-2.84)

0.02

   Model 2-adjusted OR (95% CI)

1

(referent)

0.88

(0.47-1.66)

1.56

(0.88-2.77)

1.39

(0.79-2.45)

1.52

(0.87-2.66)

0.04

   Model 3-adjusted OR (95% CI)

1

(referent)

0.87

(0.46-1.63)

1.53

(0.86-2.72)

1.36

(0.77-2.41)

1.47

(0.84-2.58)

0.06

Ischemic stroke, n

4

11

17

25

33

 

   Model 1-adjusted OR (95% CI)

1

(referent)

2.21

(0.70-7.05)

3.54

(1.17-10.67)

4.48

(1.53-13.09)

4.70

(1.62-13.61)

< 0.001

   Model 2-adjusted OR (95% CI)

1

(referent)

1.94

(0.60-6.23)

3.36

(1.11-10.22)

3.87

(1.31-11.39)

3.97

(1.36-11.61)

0.002

   Model 3-adjusted OR (95% CI)

1

(referent)

1.84

(0.57-5.96)

3.26

(1.07-9.92)

3.66

(1.24-10.79)

3.59

(1.22-10.55)

0.006

Hemorrhagic stroke, n

9

7

9

7

11

 

   Model 1-adjusted OR (95% CI)

1

(referent)

0.70

(0.26-1.92)

0.93

(0.36-2.37)

0.66

(0.24-1.80)

0.89

(0.36-2.23)

0.83

   Model 2-adjusted OR (95% CI)

1

(referent)

0.70

(0.26-1.92)

1.02

(0.39-2.64)

0.70

(0.25-1.93)

0.98

(0.38-2.50)

0.99

   Model 3-adjusted OR (95% CI)

1

(referent)

0.69

(0.25-1.90)

1.00

(0.39-2.60)

0.69

(0.25-1.90)

0.96

(0.37-2.46)

0.97

Coronary heart disease, n

9

6

12

11

17

 

   Model 1-adjusted OR (95% CI)

1

(referent)

0.55

(0.19-1.57)

1.13

(0.47-2.73)

0.88

(0.36-2.18)

1.11

(0.48-2.59)

0.48

   Model 2-adjusted OR (95% CI)

1

(referent)

0.48

(0.16-1.41)

1.20

(0.49-2.95)

0.79

(0.31-1.99)

1.05

(0.44-2.50)

0.53

   Model 3-adjusted OR (95% CI)

1

(referent)

0.49

(0.17-1.42)

1.21

(0.49-2.97)

0.80

(0.32-2.02)

1.09

(0.45-2.59)

0.49

  1. OR: odds ratio; CI: confidence interval. Model 1: adjustment was made for age and sex; Model 2: adjustment was made for age, sex, body mass index, diabetes, total cholesterol, HDL cholesterol, systolic blood pressure, electrocardiographic abnormalities, current drinking, current smoking, and regular exercise; Model 3: adjustment was made for the variables used in Model 2 and for high sensitivity C-reactive protein.