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Table 1 Characteristics of the study population:

From: MMP-1 serum levels predict coronary atherosclerosis in humans

Characteristics:

n = 260

Age (yrs)

63 (54 - 69)

Men (%)

66.8

Classical CV-Risk Factors (%)

 

   Diabetes*

6.2

   Hypertension*

47.3

   Family history of CAD**

26.9

   Smoking**

15

Body Mass Index (kg/m2)

26.2 (24.2 - 29.3)

Laboratory profile

 

   Total cholesterol (mg/dl)

209 (181.2 - 239)

   LDL cholesterol (mg/dl)

125 (96.7 - 151)

   HDL cholesterol (mg/dl)

52 (44 - 60)

   Triglycerides (mg/dl)

141 (103 - 197.5)

   C-reactive protein (mg/dl)

0.23 (0 - 0.53)

   Adiponectin (ug/ml)

5.05 (3.25 - 7.67)

   MMP-1 (ng/ml)

3.91 (2.24 - 5.67)

   MMP-9 (ng/ml)

211.3 (147.1 - 283)

Medical treatment (%)***

 

   Statin

37.7

   Anticoagulation/Antiplatelet

63.5

   Betablocker

64.9

   ACE-I or ARB

51.8

   Diuretics

30.6

CT data

 

   Pericardial adipose tissue in volume (ml)§

184.1 (128.6 - 255.8)

   Number of coronary artery plaques (total)§§

3 (1 - 6)

Number of calcified plaques (154 patients)

1 (0 - 3)

Number of mixed plaques (102 patients)

0 (0 - 1)

Number of non-calcified plaques (126 patients)

0 (0 - 2)

  1. Anticoagulation: Aspirin, Clopidogrel, Phenprocoumon
  2. Values are presented as proportions or median (interquartile range). Minimum/maximum values are presented for plaque data. No plaques were found in 51 patients.
  3. * history of hypertension and diabetes is known in 236 patients
  4. ** history of smoking and family history of CAD is known in 235 patients
  5. *** medical treatment is known in 222 patients
  6. §adequate image quality for evaluation of PAT was obtained in 248 patients
  7. §§ adequate image quality for evaluation of coronary plaques was obtained in 242 patients