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Table 5 Changes in the levels of ProBNP from baseline to 2 year follow-up -bezafibrate vs placebo-

From: Long-term effects of peroxisome proliferator-activated receptor ligand bezafibrate on N-terminal pro-B type natriuretic peptide in patients with advanced functional capacity impairment

 

Bezafibrate

(n = 58)

Placebo

(n = 50)

Absolute change

  

   Mean ± SD

120 ± 524

58 ± 307

   Median (Interquartile range)

25 (-14–141)

-20 (-102–87)

P = 0.02 (Kruskal-Wallis test, unadjusted)

Percent change

  

   Geometric mean (95% CI)

34.1 (8.0–66.3)

-4.3 (-21.8–17.0)

   Median (Interquartile range)

21.9 (-9.0–111.8)

-15.8 (-33.1–46.6)

P = 0.3 (ANCOVA, adjusted for age and baseline ProBNP levels)

P = 0.01 (Kruskal-Wallis test, unadjusted)