Different modulation by dietary restriction of adipokine expression in white adipose tissue sites in the rat

Table 4 Statistical significance of the correlations of the serum levels of glucose, lipids, insulin, leptin and adiponectin versus the combined four-site WAT specific mRNA content for peptidic signaling agents and total four-site WAT weight or perilipin expression (r² and P values)

adipokine gene expression		total site mRNA copies versus serum levels
adipokine gene expression		cholesterol	NEFA	TAG	glucose	insulin	leptin	adiponectin
total WAT weight	r²	NS	NS	0.687	0.442	0.985	0.940	NS
	P			0.0030	0.0257	0.0065	0.0016
perilipin	r²	NS	NS	0.391	0.436	0.777	0.835	NS
	P			0.0391	0.0259	0.0390	0.0194
leptin	r²	NS	NS	0.543	0.488	0.934	0.969	NS
	P			0.0097	0.0167	0.0020	0.0003
VEGF-A	r²	NS	NS	0.497	0.464	0.892	0.931	NS
	P			0.0154	0.0210	0.0069	0.0023
resistin	r²	NS	NS	NS	NS	0.885	0.916	NS
	P					0.0081	0.0037
adiponectin	r²	NS	NS	0.400	NS	NS	NS	NS
	P			0.0491
visfatin	r²	NS	NS	0.419	NS	NS	NS	NS
	P			0.0312
TNFα	r²	NS	NS	NS	NS	NS	NS	NS
	P
interleukin 1β	r²	NS	NS	NS	NS	0.771	0.834	NS
	P					0.0424	0.0197
interleukin 6	r²	NS	NS	NS	NS	NS	NS	NS
	P
PAI-1	r²	NS	NS	NS	NS	0.822	0.931	NS
	P					0.0233	0.0468
CD68	r²	NS	NS	0.425	NS	NS	NS	NS
	P			0.0298
MCP1	r²	NS	NS	0.628	0.389	0.784	0.842	NS
	P			0.0036	0.0403	0.0371	0.0175

The data were calculated taking into account the sum of the four sites for all samples (i.e. from both experimental groups) as a whole. All correlations were positive. TAG = triacylglycerols; NEFA = non-esterified fatty acids. NS = P < 0.05.

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