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Figure 3 | Cardiovascular Diabetology

Figure 3

From: Altered myocardial substrate metabolism is associated with myocardial dysfunction in early diabetic cardiomyopathy in rats: studies using positron emission tomography

Figure 3

Molecular alterations in ZDF hearts. Quantification of glucose transporter-4 (GLUT4) mRNA levels (A) and protein levels (B), pyruvate dehydrogenase 4 (PDK4) protein levels (C) and phosphorylation/total protein levels of AMP kinase a (AMPKα1/2-Thr172) (D) in ZL rats (open bars) and ZDF rats (filled bars). Protein expression and a typical example of subcellular localisation of the fatty acid transporter (FAT)/CD36 (E) in ZL rats and ZDF rats. Data are expressed as mean ± SEM, n = 4–8, * p < 0.05, # p = 0.10.

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