| |
Baseline
|
3 months
|
6 months
|
P*
|
|---|
|
HbA1C (%, Mono-S)
|
6.6 ± 0.6
|
5.9 ± 0.9
|
5.6 ± 0.6
|
0.10
|
|
Cholesterol (mmol/l)
|
4.4 ± 1.1
|
4.4 ± 1.1
|
4.3 ± 1.3
|
0.6
|
|
LDL (mmol/l)
|
2.9 ± 0.9
|
2.8 ± 1.0
|
2.7 ± 1.0
|
0.5
|
|
HDL (mmol/l)
|
1.3 ± 0.2
|
1.3 ± 0.3
|
1.3 ± 0.3
|
0.9
|
|
TG (mmol/l)
|
1.5 ± 0.7
|
1.3 ± 0.7
|
1.2 ± 0.5
|
0.5
|
|
CRP (mg/l)
|
2.4 ± 1.8
|
2.8 ± 2.5
|
1.8 ± 1.0
|
0.14
|
|
SBP (mmHg)
|
150 ± 21
|
144 ± 16
|
145 ± 21
|
0.9
|
|
DBP (mmHg)
|
83 ± 8
|
80 ± 8
|
82 ± 8
|
0.4
|
|
Weight (kg)
|
87 ± 17
|
83 ± 15
|
82 ± 12
|
0.4
|
|
BMI (kg/m2)
|
30 ± 7
|
29 ± 6
|
28 ± 4
|
0.4
|
|
Waist (cm)
|
103 ± 14
|
96.8 ± 12
|
95 ± 9
|
0.5
|
|
fP-glucose (mmol/l)
|
7.8 ± 1.2
|
7.1 ± 1.6
|
7.3 ± 1.3
|
0.5
|
|
fP-insulin (pmol/l)
|
98 ± 44
|
74 ± 28
|
63 ± 21
|
0.2
|
|
AUC glucose (mmol/l·min)
|
1607 ± 218
|
1438 ± 350
|
1437 ± 329
|
1.0
|
|
AUC glucose (mmol/l·min)1
|
667 ± 186
|
583 ± 189
|
558 ± 219
|
0.6
|
|
AUC insulin (nmol/l·min)
|
30 ± 12
|
29 ± 12
|
23 ± 14
|
0.01
|
|
AUC insulin (nmol/l·min)1
|
18 ± 8
|
21 ± 11
|
16 ± 13
|
0.01
|
|
ISI0,120 (mg·l2/mmol·mU·min)
|
40 ± 9
|
50 ± 16
|
56 ± 25
|
0.2
|
|
HOMA2 %B
|
65 ± 34
|
65 ± 27
|
53 ± 18
|
0.04
|
|
HOMA2 %S
|
59 ± 27
|
80 ± 42
|
87 ± 28
|
0.6
|
|
HOMA2 IR
|
2.0 ± 0.8
|
1.5 ± 0.6
|
1.3 ± 0.4
|
0.2
|
|
Diabetic values at OGTT yes/no (n)
|
12/1
|
8/5
|
9/4
|
1.0
|
- *P for difference between 3 and 6 months in a two-sided t-test with dependent samples, except for Diabetic values at OGTT where P is for difference between diets in Fischer's two-sided exact test with related samples. 1stimulated secretion, area under curve at OGTT with value at 0 minutes as baseline.
