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Table 1 Metabolic characteristics of normoglycemic (group N), normoglycemic, in vivo losartan treated (group NL), diabetic (group D) and diabetic, in vivo losartan treated (group DL) rats.

From: Losartan counteracts the hyper-reactivity to angiotensin II and ROCK1 over-activation in aortas isolated from streptozotocin-injected diabetic rats

Groups

Plasma Glycemia

(mM)

Daily Water Consumption (ml)

Daily Food Intake

(g)

Body Weight

(g)

Heart Wet Weight

(mg)

Heart Weight/Body Weight

(mg/g)

N (n = 7)

7.0 ± 0.014

29.9 ± 2.2

17.9 ± 0.8

262.1 ± 10.1

993.8 ± 37

3.8 ± 0.2

NL (n = 7)

9.0 ± 0.033

29.3 ± 1.6

19.4 ± 0.5

254.7 ± 9.1

951.3 ± 36

3.7 ± 0.1

D (n = 14)

20.0 ± 0.18*

133.8 ± 6.8*

28.6 ± 0.9*

217.6 ± 5.4*

806.5 ± 33^

3.7 ± 0.1

DL (n = 12)

18.7 ± 0.25#

130.1 ± 8.6#

27.3 ± 1.4#

207.5 ± 10.2#

851.5 ± 60

4.1 ± 0.4

  1. Values presented are the mean ± SEM of the indicated number of rats (n). P < 0.001 vs. N; # P < 0.001 vs. NL; ^P < 0.01 vs. N. Wistar rats aged 12–14 weeks were randomly assigned to the different groups.