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Figure 2 | Cardiovascular Diabetology

Figure 2

From: Losartan counteracts the hyper-reactivity to angiotensin II and ROCK1 over-activation in aortas isolated from streptozotocin-injected diabetic rats

Figure 2

The effect of angiotensin-II in aortic strips isolated from normoglycemic (group N), normoglycemic in vivo losartan treated (group NL), diabetic (group D) and in vivo losartan treated diabetic rats (group DL). Cumulative concentration-response curves of angiotensin II (bolus) were performed on 100 nM phenylephryne (Phe) pre-contracted thoracic aortic strips stretched to 0.7 g resting tension with an endothelial-intact layer. Values are the mean ± SEM of 4 experiments. ***P < 0.001 vs. N and NL; §§§P < 0.001 vs. DL

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Cardiovascular Diabetology

ISSN: 1475-2840