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Table 2 Parameters of hemostasis, rheology, fibrinolysis, platelet activation and extent and severity of coronary atherosclerosis

From: Relevance of hemostatic risk factors on coronary morphology in patients with diabetes mellitus type 2

  all patients Diabetes mellitus Typ II control patients p-value
  (n = 150) (n = 26) (n = 122)  
hemostasis
fibrinogen (mg/dl) 282 ± 64 295 ± 76 278 ± 61 0.1618
prothrombinfragment 1 + 2 (μg/dl) 0,99 ± 0,52 1,01 ± 0,55 0,87 ± 0,37 0.0622
D-Dimere (μg/l) 35 ± 62 31 ± 43 36 ± 65 0.5519
Thrombin-Antithrombin-Komplex (μg/l) 7,6 ± 16 9,6 ± 18,7 7,3 ± 15,5 0.5221
Rheology
plasma viscosity (mPas) 1,30 ± 0,09 1,33 ± 0,09 1,29 ± 0,09 0.0933
erythocyte aggregation M (E) 6,3 ± 1,8 7,3 ± 1,9 6,1 ± 1,8 0.0026
erythocyte aggregation M1 (E) 11,3 ± 2,5 12,8 ± 2,7 11,0 ± 2,3 0.0013
hematocrit (%) 43,5 ± 3,1 42,7 ± 3,7 43,6 ± 2,9 0.1537
fibrinolysis
tissue-plasminogenaktivator (ng/dl) 13,47 ± 3,68 14,18 ± 3,36 13,30 ± 3,77 0.4394
plasminogenactivatorinhibitor (U/ml) 5,78 ± 3,25 7,36 ± 3,24 5,45 ± 3,18 0.0017
plasmin-α2-antiplasmin-complex (μg/dl) 395 ± 152 378 ± 168 396 ± 146 0.4245
platelet activation
platelet count (100.000/ml) 246 ± 71 265 ± 71 242 ± 71 0.1727
von Willebrand-factor (μg/l) 94 ± 31 99 ± 32 93 ± 30 0.3661
plateletfactor 4 (μg/l) 12,7 ± 18,8 9,2 ± 10,9 13,4 ± 20,1 0.9104
β-thromboglobulin (μg/l) 36,68 ± 41,90 30,07 ± 17,57 38,28 ± 45,53 0.7181
GMP 140 (μg/l) 96,36 ± 44,69 94,64 ± 23,41 96,88 ± 48,26 0.2773
Extent and severity of coronary atherosclerosis
total score 1,451 ± 0,591 1,858 ± 0,680 1,379 ± 0,550 0.0182
proximal score 1,399 ± 0,696 1,775 ± 1,037 1,333 ± 0,607 0.2363
distal score 1,457 ± 0,666 1,874 ± 0,647 1,388 ± 0,651 0.0109
1-vessel CAD 31.0% 12.0% 35.0%  
2-vessel CAD 37.0% 39.0% 37.0%  
3-vessel CAD 32.0% 50.0% 28.0% 0.0306