Blood pressure reduction, persistence and costs in the evaluation of antihypertensive drug treatment – a review

Table 6 Disease-Related Healthcare Costs and Hospitalization Risk at Varying Levels of Medication Adherence [24]

Adherence Level	N	Medical Costs ($)	Drug Costs ($)	Total Costs ($)	Hospitalization Risk (%)
1–19	350	4847	31	4878	28
20–39	344	5973	89	6062	24
40–59	562	5113	184	5297	24
60–79	921	4977	285	5262	20
80–100	5804	4383	489	4871	19
		F = 46.44**	F = 171.98**		X2 (31 df) = 1256.3**
		Adj. r ² = 0.13	Adj. r ² = 0.37

CI, confidence interval; *Indicates that the outcome is significantly higher than the outcome for the 80–100% adherence group (P < 0.05). Differences were tested for medical cost and hospitalization risk; ** p < 0.0001