Table 2 Average reduction in blood pressure over 24 hours (treated minus placebo) according to category of drug and dose [9]
Drugs | Systolic/Diastolic | Fall in blood pressure (mmHg (95%CI)) |
|---|---|---|
Thiazides | Systolic | 8.8 (8.3 to 9.4) |
Diastolic | 4.4 (4.0 to 4.8) | |
Beta-blockers | Systolic | 9.2 (8.6 to 9.9) |
Diastolic | 6.7 (6.2 to 7.1) | |
ACE inhibitors | Systolic | 8.5 (7.9 to 9.0) |
Diastolic | 4.7 (4.4 to 5.0) | |
Angiotensin II receptor antagonists | Systolic | 10.3 (9.9 to 10.8) |
Diastolic | 5.7 (5.4 to 9.0) | |
Calcium channel blockers | Systolic | 8.8 (8.3 to 9.2) |
Diastolic | 5.9 (5.6 to 6.2) |