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Table 4 Evolution of plasma TAG and NEFA (measured in the fed state) in control rats and in ZDF rats receiving or not fenofibrate (F) or metformin (M).

From: Diabetic cardiomyopathy: effects of fenofibrate and metformin in an experimental model – the Zucker diabetic rat

TAG mM Control ZDF ZDF + F ZDF + M
7 weeks 0.89 ± 0.06 2.85 ± 0.39 *** 4.09 ± 0.44 *** 3.32 ± 0.29 ***
14 weeks 1.34 ± 0.08 10.40 ± 1.10 *** 6.50 ± 1.19 ***$ 8.60 ± 1.07 ***
21 weeks 1.50 ± 0.12 9.86 ± 0.63 *** 12.10 ± 1.42 *** 13.20 ± 0.57 ***
NEFA μM     
7 weeks 550 ± 62 435 ± 43 541 ± 64 523 ± 89
14 weeks 541 ± 64 1062 ± 103 *** 869 ± 107 *** 1098 ± 123 **
21 weeks 416 ± 27 824 ± 115 ** 1121 ± 145 *** 1211 ± 104 ***
  1. Results are shown are mean and sem** p < 0.01, *** p < 0.001 vs the corresponding control group; $ p < 0.05 vs the corresponding ZDF group.