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Table 1 Evolution of food intake and of body weight in control rats and in ZDF rats receiving or not fenofibrate (F) or metformin (M).

From: Diabetic cardiomyopathy: effects of fenofibrate and metformin in an experimental model – the Zucker diabetic rat

Food intake (g/day) Control ZDF ZDF + F ZDF + M
7 weeks 18.5 ± 0.4 27.5 ± 0.7 *** 26.7 ± 0.7*** 26.3 ± 0.6***
14 weeks 26.5 ± 0.9 46.9 ± 2.4*** 43.5 ± 2.4*** 47.1 ± 2.1***
21 weeks 26.6 ± 1.0 46.5 ± 3.0 *** 46.9 ± 3.7*** 43.8 ± 2.2***
Body weight (g)     
7 weeks 188 ± 4 231 ± 5*** 253 ± 11*** 228 ± 8**
14 weeks 325 ± 14 345 ± 5 314 ± 5$ 360 ± 13
21 weeks 409 ± 9 361 ± 6** 326 ± 8***$ 398 ± 25
  1. Results are shown are mean and sem. * p < 0.05, ** p < 0.01, *** p < 0.001 vs the corresponding control; $ p < 0.05 vs the corresponding ZDF group.
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Cardiovascular Diabetology

ISSN: 1475-2840