Table 1 Evolution of food intake and of body weight in control rats and in ZDF rats receiving or not fenofibrate (F) or metformin (M).
Food intake (g/day) | Control | ZDF | ZDF + F | ZDF + M |
|---|---|---|---|---|
7 weeks | 18.5 ± 0.4 | 27.5 ± 0.7 *** | 26.7 ± 0.7*** | 26.3 ± 0.6*** |
14 weeks | 26.5 ± 0.9 | 46.9 ± 2.4*** | 43.5 ± 2.4*** | 47.1 ± 2.1*** |
21 weeks | 26.6 ± 1.0 | 46.5 ± 3.0 *** | 46.9 ± 3.7*** | 43.8 ± 2.2*** |
Body weight (g) | ||||
7 weeks | 188 ± 4 | 231 ± 5*** | 253 ± 11*** | 228 ± 8** |
14 weeks | 325 ± 14 | 345 ± 5 | 314 ± 5$ | 360 ± 13 |
21 weeks | 409 ± 9 | 361 ± 6** | 326 ± 8***$ | 398 ± 25 |