Table 1 Subjects' anthropometric and laboratory characteristics at baseline and after 26 weeks of treatment.

15

15

Men/women

11/4

9/6

Age(years)

60.8 ± 7.1

61.5 ± 8.2

Diabetes Duration (years)

11.1 ± 6

9.5 ± 7.5

BMI (kg/m²)

30.8 ± 5.5

31.9 ± 5.9

0.001

31.6 ± 6.1

32.5 ± 6.2

0.01

0.37

HbA_1c (%)

8.1 ± 1.5

6.8 ± 1.2

0.001

8.3 ± 1.4

6.1 ± 0.7

0.001

0.23

Haemoglobin (g/l)

137.5 ± 11.4

127 ± 12.0

0.001

137.1 ± 10.2

132 ± 12.0

0.02

0.13

Cholesterol (mmol/l)

4.4 ± 0.9

4.2 ± 0.7

0.17

4.3 ± 1.0

4.1 ± 1.0

0.32

0.65

HDL (mmol/l)

1.1 ± 0.2

1.3 ± 0.3

0.01

1.1 ± 0.4

1.1 ± 0.4

0.49

0.01

LDL (mmol/l)

2.4 ± 0.9

2.3 ± 0.5

0.64

2.3 ± 0.7

2.4 ± 0.7

0.46

0.48

TG (mmol/l)

1.8 ± 0.8

1.5 ± 1.0

0.002

1.9 ± 1.3

1.5 ± 1.0

0.009

0.43

ALT (μcat/l)

0.7 ± 0.7

0.4 ± 0.3

0.04

0.5 ± 0.2

0.5 ± 0.2

0.12

0.87

Systolic blood pressure

142 ± 16

134 ± 10

0.04

146 ± 17

132 ± 13

0.02

0.39

Diastolic blood pressure

84 ± 8

77 ± 7

0.02

81 ± 8

73 ± 8

0.007

0.57

BNP (pmol/l)

6.9 ± 5.2

14.1 ± 16.7

0.10

9.7 ± 12.9

9.7 ± 11.6

0.41

0.51

NT-proBNP (ng/l)

11.4 ± 19.6

22.8 ± 44.0

0.046

13.6 ± 20.0

10.1 ± 9.5

0.97

0.23