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Table 3 Cost inputs: US perspective

From: Long-term outcomes in patients with type 2 diabetes receiving glimepiride combined with liraglutide or rosiglitazone

 

Values

Units

Reference

Discount rates

   

Discount clinical

0.00

 

41

Discount costs

0.03

 

41

Management costs

   

Annual statins

947.74

US$

42

Annual cost aspirin

23.01

US$

42

Annual cost ACE

426.21

US$

42

Annual cost screening for microalbuminuria

18.62

US$

10

Annual cost screening for GFR

27.4

US$

10

Stopping ACEs due to adverse events

0

US$

NA

Annual cost of eye screening

82.18

US$

10

Foot screening program (monthly based)

0

US$

NA

Non-standard ulcer treatment (e.g. topical becaplermin) (monthly based)

167.64

US$

43

Costs for CVD complications

   

MI year 1

37,421

US$

10

MI year 2 and onwards

2,069

US$

10

Angina year 1

7,424

US$

10

Angina year 2 and onwards

1,917

US$

10

CHF year 1

3,214

US$

10

CHF year 2 and onwards

3,214

US$

10

Stroke year 1

49,556

US$

10

Stroke year 2 and onwards

16,539

US$

10

Stroke death within 30 days

0

US$

NA

PVD year 1

4,707

US$

44

PVD year 2 and onwards

4,707

US$

44

Costs: renal complications

   

Hemodialysis costs year 1

45,638

US$

10

Annual costs HD year 2 and onwards

45,638

US$

10

Peritoneal dialysis costs year 1

45,638

US$

10

Annual costs PD year 2 and onwards

45,638

US$

10

Renal transplant costs year 1

45,638

US$

10

Annual costs year 2 and onwards

0

US$

NA

Costs: acute events

   

Major hypoglycemic event

1,191

US$

10

Ketoacidosis event

13,404

US$

10

Lactic acid event

0

US$

NA

Costs: eye disease

   

Laser treatment

834

US$

10

Cataract operation

2,655

US$

10

Annual costs following cataract operation

0

US$

44

Blindness year 1

4,039

US$

10

Blindness year 2 and onwards

4,039

US$

10

Costs neuropathy/foot ulcer/amputation

   

Neuropathy year 1

408

US$

10

Neuropathy year 2 and onwards

408

US$

10

Amputation (event-based)

33,257

US$

10

Amputation prosthesis (event based)

1,195

US$

10

Gangrene treatment (monthly based)

6,240

US$

45

After healed ulcer (yearly based)

0

US$

NA

Infected ulcer (monthly based)

3,198

US$

45

Standard uninfected ulcer (monthly based)

1,769

US$

45

Healed ulcer history of amputation (yearly based)

0

US$

NA

  1. ACE, angiotensin-converting enzyme; CHF, congestive heart failure; CVD, cardiovascular disease; GFR, glomerular filtration rate; MI, myocardial infarction; PVD, peripheral vascular disease.