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Table 4 Allelic distribution of RAAS gene polymorphisms in gender

From: Analysis of renin-angiotensin aldosterone system gene polymorphisms in malaysian essential hypertensive and type 2 diabetic subjects

Alleles of RAAS Gene Polymorphisms   Group 1 Group 2 Group 3 Group 4
Male Female Male Female Male Female Male Female
A6G C 76
(78.40)
26
(21.60)
60
(90.90)
6
(9.10)
61
(76.25)
19
(23.75)
74
(94.87)
4
(5.13)
T 30
(89.50)
8
(10.50)
47
(87.04)
7
(12.96)
36
(65.45)
14
(25.45)
68
(94.44)
4
5.56)
p value
OR (95% CI)
0.662
0.78 (0.318–1.914)
0.563
1.49 (0.469–4.729)
0.680
1.25 (0.559–2.790)
1.000
1.09 (0.262–4.522)
A20C A 82
(80.40)
20
(19.60)
55
(83.30)
11
(16.70)
70
(87.50)
10
(12.50)
67
(85.90)
11
(14.10)
C 31
(81.60)
7
(18.40)
41
(76.00)
13
(24.00)
39
(78.00)
11
(22.00)
60
(83.33)
12
(1.67)
p value
OR (95% CI)
1.000
0.93 (0.356–2.045)
0.363
1.59 (0.645–3.896)
0.220
1.97 (0.770–5.063)
0.821
1.22 (0.501–2.964)
MboI (-) 85
(83.33)
17
(16.67)
58
(87.88)
8
(12.12)
66
(82.50)
14
(17.50)
65
(83.33)
13
(16.67)
(+) 29
(76.32)
9
(23.68)
44
(81.48)
10
(18.52)
43
(86.00)
7
(14.00)
65
(90.28)
7
(9.72)
p value
OR (95% CI)
0.339
1.55 (0.624–3.860)
0.442
1.65 (0.601–4.519)
0.635
0.77 (0.287–2.056)
0.238
0.54 (0.202–1.436)
Lys173Arg Lys173 76 (74.51) 26 (25.49) 44 (66.70) 22 (33.30) 59 (73.75) 21 (26.25) 58 (74.36) 20 (25.64)
Arg173 29 (76.30) 9
(23.70)
37 (68.52) 17 (31.48) 39 (78.00) 11 (22.00) 53 (73.61) 19 (26.39)
p value
OR (95% CI)
1.000
0.90 (0.380–2.166)
0.847
0.92 (0.426–1.983)
0.678
0.79 (0.344–1.825)
1.000
1.04 (0.501–2.157)
Gly460Trp Gly460 66
(64.71)
36
(35.29)
42
(63.64)
24
(36.36)
46
(57.50)
34
(42.50)
52
(69.30)
26
(30.70)
Trp460 19
(50.00)
19
(50.00)
35
(64.81)
19
(35.19)
23
(46.00)
27
(54.00)
44
(61.11)
28
(38.89)
p value
OR (95% CI)
0.124
1.88 (0.862–3.899)
0.893
0.95 (0.458–2.012)
0.201
1.59 (0.780–3.234)
0.479
1.27 (0.653–2.482)
  1. Data are reported as number of subjects with percent in parentheses, OR-odds ratio, CI – Confidence interval, Group 1- EHT, Group 2 -T2DM, Group 3- EHT+T2DM and Group 4-Control subjects, P value > 0.05 vs. Group 4.