Alleles of RAAS Gene Polymorphisms | Â | Group 1 | Group 2 | Group 3 | Group 4 | ||||
---|---|---|---|---|---|---|---|---|---|
Male | Female | Male | Female | Male | Female | Male | Female | ||
A6G | C | 76 (78.40) | 26 (21.60) | 60 (90.90) | 6 (9.10) | 61 (76.25) | 19 (23.75) | 74 (94.87) | 4 (5.13) |
T | 30 (89.50) | 8 (10.50) | 47 (87.04) | 7 (12.96) | 36 (65.45) | 14 (25.45) | 68 (94.44) | 4 5.56) | |
p value OR (95% CI) | 0.662 0.78 (0.318–1.914) | 0.563 1.49 (0.469–4.729) | 0.680 1.25 (0.559–2.790) | 1.000 1.09 (0.262–4.522) | |||||
A20C | A | 82 (80.40) | 20 (19.60) | 55 (83.30) | 11 (16.70) | 70 (87.50) | 10 (12.50) | 67 (85.90) | 11 (14.10) |
C | 31 (81.60) | 7 (18.40) | 41 (76.00) | 13 (24.00) | 39 (78.00) | 11 (22.00) | 60 (83.33) | 12 (1.67) | |
p value OR (95% CI) | 1.000 0.93 (0.356–2.045) | 0.363 1.59 (0.645–3.896) | 0.220 1.97 (0.770–5.063) | 0.821 1.22 (0.501–2.964) | |||||
MboI | (-) | 85 (83.33) | 17 (16.67) | 58 (87.88) | 8 (12.12) | 66 (82.50) | 14 (17.50) | 65 (83.33) | 13 (16.67) |
(+) | 29 (76.32) | 9 (23.68) | 44 (81.48) | 10 (18.52) | 43 (86.00) | 7 (14.00) | 65 (90.28) | 7 (9.72) | |
p value OR (95% CI) | 0.339 1.55 (0.624–3.860) | 0.442 1.65 (0.601–4.519) | 0.635 0.77 (0.287–2.056) | 0.238 0.54 (0.202–1.436) | |||||
Lys173Arg | Lys173 | 76 (74.51) | 26 (25.49) | 44 (66.70) | 22 (33.30) | 59 (73.75) | 21 (26.25) | 58 (74.36) | 20 (25.64) |
Arg173 | 29 (76.30) | 9 (23.70) | 37 (68.52) | 17 (31.48) | 39 (78.00) | 11 (22.00) | 53 (73.61) | 19 (26.39) | |
p value OR (95% CI) | 1.000 0.90 (0.380–2.166) | 0.847 0.92 (0.426–1.983) | 0.678 0.79 (0.344–1.825) | 1.000 1.04 (0.501–2.157) | |||||
Gly460Trp | Gly460 | 66 (64.71) | 36 (35.29) | 42 (63.64) | 24 (36.36) | 46 (57.50) | 34 (42.50) | 52 (69.30) | 26 (30.70) |
Trp460 | 19 (50.00) | 19 (50.00) | 35 (64.81) | 19 (35.19) | 23 (46.00) | 27 (54.00) | 44 (61.11) | 28 (38.89) | |
p value OR (95% CI) | 0.124 1.88 (0.862–3.899) | 0.893 0.95 (0.458–2.012) | 0.201 1.59 (0.780–3.234) | 0.479 1.27 (0.653–2.482) |