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Table 1 Clinical and biochemical data of subjects

From: Association between the FTO rs9939609 polymorphism and the metabolic syndrome in a non-Caucasian multi-ethnic sample

Greenland Inuit

Male

Female

P-value

n = 486

n = 622

 

age (years)

46.2 ± 12.9

45.8 ± 13.1

NS (0.60)

BMI (kg/m2)

26.2 ± 4.6

26.7 ± 5.42

NS (0.072)

waist (cm)

91.1 ± 12.2

88.1 ± 13.5

0.0001

systolic BP (mmHg)

120 ± 17

119 ± 20

NS (0.14)

diastolic BP (mmHg)

74 ± 11

72 ± 11

<0.0001

total cholesterol (mmol/L)

5.99 ± 1.18

6.02 ± 1.13

NS (0.77)

triglycerides (mmol/L)

1.15 ± 0.66

1.12 ± 0.61

NS (0.090)

LDL cholesterol (mmol/L)

3.90 ± 1.091

3.89 ± 1.062

NS (0.67)

HDL cholesterol (mmol/L)

1.56 ± 0.49

1.62 ± 0.42

0.0015

fasting glucose (mmol/L)

5.83 ± 0.89

5.76 ± 1.34

NS (0.21)

MetS (%)

12.1

17.0

0.017

Oji-Cree

n = 218

n = 291

 

age (years)

35.9 ± 14.5

35.7 ± 14.7

NS (0.85)

BMI (kg/m2)

26.8 ± 4.6

29.1 ± 5.5

<0.0001

waist (cm)

96.9 ± 12.2

95.0 ± 11.9

NS (0.073)

systolic BP (mmHg)

122 ± 14

118 ± 16

<0.0001

diastolic BP (mmHg)

70 ± 12

67 ± 10

<0.0001

total cholesterol (mmol/L)

4.83 ± 0.98

4.59 ± 0.82

0.0001

triglycerides (mmol/L)

1.63 ± 0.85

1.51 ± 0.71

0.0003

LDL cholesterol (mmol/L)

2.91 ± 0.823

2.62 ± 0.654

<0.0001

HDL cholesterol (mmol/L)

1.19 ± 0.30

1.28 ± 0.28

<0.0001

fasting glucose (mmol/L)

6.73 ± 3.25

6.77 ± 3.50

NS (0.61)

MetS (%)

30.3

39.2

0.028

South Asian

n = 180

n = 147

 

age (years)

49.9 ± 8.9

49.0 ± 9.6

NS (0.37)

BMI (kg/m2)

26.1 ± 4.35

26.5 ± 3.8

NS (0.37)

waist (cm)

94.7 ± 9.7

86.0 ± 10.6

<0.0001

systolic BP (mmHg)

121 ± 16

117 ± 19

0.034

diastolic BP (mmHg)

80 ± 12

71 ± 10

<0.0001

total cholesterol (mmol/L)

5.26 ± 0.98

5.15 ± 0.94

NS (0.41)

triglycerides (mmol/L)

2.05 ± 1.31

1.92 ± 1.27

NS (0.30)

LDL cholesterol (mmol/L)

3.45 ± 0.846

3.18 ± 0.797

0.0069

HDL cholesterol (mmol/L)

0.95 ± 0.26

1.13 ± 0.32

<0.0001

fasting glucose (mmol/L)

5.95 ± 1.89

5.49 ± 1.58

0.020

MetS (%)

31.1

34.0

NS (0.38)

Chinese

n = 148

n = 151

 

age (years)

48.8 ± 9.3

46.6 ± 8.4

0.030

BMI (kg/m2)

25.2 ± 3.4

22.7 ± 3.5

<0.0001

waist (cm)

89.6 ± 9.1

75.2 ± 7.9

<0.0001

systolic BP (mmHg)

122 ± 17

112 ± 20

0.022

diastolic BP (mmHg)

80 ± 10

70 ± 12

<0.0001

total cholesterol (mmol/L)

5.29 ± 1.00

4.85 ± 0.84

0.0057

triglycerides (mmol/L)

2.14 ± 1.61

1.38 ± 1.03

0.0055

LDL cholesterol (mmol/L)

3.34 ± 0.848

2.90 ± 0.719

0.0006

HDL cholesterol (mmol/L)

1.03 ± 0.29

1.33 ± 0.36

<0.0001

fasting glucose (mmol/L)

5.44 ± 1.29

4.98 ± 0.60

0.016

MetS (%)

28.4

10.6

0.0003

  1. 1n = 483, 2n = 620, 3n = 216, 4n = 289, 5n = 179, 6n = 169, 7n = 141, 8n = 139, 9n = 148
  2. Abbreviations: BMI, body mass index; BP, blood pressure; LDL, low-density lipoprotein; HDL, high-density lipoprotein; MetS, metabolic syndrome; NS, not significant.
  3. Data are means ± standard deviation (SD). P-values are adjusted for age; P-values for blood pressure, cholesterol, triglycerides, LDL cholesterol, HDL cholesterol, and glucose are also adjusted for BMI.