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Figure 4 | Cardiovascular Diabetology

Figure 4

From: Eptifibatide and abciximab inhibit insulin-induced focal adhesion formation and proliferative responses in human aortic smooth muscle cells

Figure 4

Effect of c7E3, m7E3 and eptifibatide on insulin-induced ERK and JNK activation. Growth arrested HASMC were treated with m7E3, c7E3 or eptifibatide (indicated concentrations in A, both antibodies were used at 30 μg/ml and eptifibatide at 10 μmol/L in B and C) as indicated for one hour. Insulin (1 μmol/L) or vehicle was added and ten minutes later ERK and JNK1 activity were determined as described in Methods.

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