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Figure 2 | Cardiovascular Diabetology

Figure 2

From: Eptifibatide and abciximab inhibit insulin-induced focal adhesion formation and proliferative responses in human aortic smooth muscle cells

Figure 2

Effect of α v β 3 antagonists on insulin-induced proliferation. Growth arrested HASMC were treated with insulin (various concentrations), PDGF-BB (1.4 nmol/L) or vehicle and cell number was determined three days later (A). In the experiments represented in panels B and C, HASMC were treated with antibodies or peptides as indicated for one hour prior to addition of insulin (1 μmol/L). Concentrations of antibodies and peptides were the same as in figure 1 unless indicated. [* = p < 0.05 vs control (A); * = p < 0.05 vs 10E5 (B); * = p < 0.05 vs tirofiban (C)]

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