Table 2 Lactate:pyruvate ratios in Type 2 diabetic hearts
From: Polyol pathway and modulation of ischemia-reperfusion injury in Type 2 diabetic BBZ rat hearts
Group | n | Lactate/Pyruvate ratio |
|---|---|---|
Non-diabetic controls | 12 | 16.8 ± 3.2 |
Type 2 diabetics | ||
12 weeks duration | 9 | 41.4 ± 8.8* |
48 weeks duration | 5 | 77.5 ± 12.2* |
Aldose reductase inhibited Type 2 diabetics | ||
12 weeks duration | 7 | 7.2 ± 1.8 |
48 weeks duration | 5 | 10.5 ± 3.2 |
Sorbitol dehydrogenase inhibited Type 2 diabetics | ||
12 weeks duration | 7 | 8.9 ± 2.1 |
48 weeks duration | 5 | 12.6 ± 3.4 |