Skip to main content

Advertisement

Figure 5 | Cardiovascular Diabetology

Figure 5

From: Polyol pathway and modulation of ischemia-reperfusion injury in Type 2 diabetic BBZ rat hearts

Figure 5

(A) Lactate/pyruvate ratios in age matched non-diabetic (ND), Type 2 diabetic (BBZ), BBZ treated with aldose reductase inhibitor (BBZ-ARI), BBZ treated with sorbitol dehydrogenase inhibitor (BBZ-SDI) rat hearts at the end of ischemic period. Six hearts were studied per group. ATP, expressed as ╬╝moles/g dry wt, age matched non-diabetic (ND), Type 2 diabetic (BBZ), BBZ treated with aldose reductase inhibitor (BBZ-ARI), BBZ treated with sorbitol dehydrogenase inhibitor (BBZ-SDI) rat hearts at the end of ischemia (B), and at the end of reperfusion (C). Six hearts were studied per group. *P < 0.05 vs ND, BBZ-ARI, and BBZ-SDI comparing ATP at the end of Ischemia, #P < 0.05 vs ND, BBZ-ARI, and BBZ-SDI comparing ATP at the end of reperfusion.

Back to article page