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Figure 1 | Cardiovascular Diabetology

Figure 1

From: Polyol pathway and modulation of ischemia-reperfusion injury in Type 2 diabetic BBZ rat hearts

Figure 1

Products of polyol pathway, sorbitol (A) and fructose (B) were measured in the hearts from 12 weeks and 48 weeks diabetic (DM) BBZ rats and their age matched non-diabetic (ND) controls. Diabetes duration of 12 weeks (n = 9) and 48 weeks (n = 6) were used in this study. ARI denotes treatment with the aldose reductase inhibitor zopolrestat, while SDI denotes treatment with sorbitol dehydrogenase inhibitor.

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