Table 2 Clinical relevance of advanced glycation endproducts (AGEs)

Measure of long-term cumulative metabolic stress

AGEs as a mechanism for the "metabolic memory" observed in diabetes

Measure of oxidative stress (e.g. from smoking) and its' interaction with metabolic stress

Shows the resulting protein damage from various cardiovascular risk factors

AGEs are independent predictors of cardiovascular complications and mortality

Perioperative risk (e.g. cardiac events, pulmonary complications) is related to AGEs

AGEs may help in monitoring and tailoring diabetes treatment