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Table 2 Haemodynamic and perfusion data at baseline and during hyperaemia in controls and diabetics.

From: Effect of streptozotocin-induced diabetes on myocardial blood flow reserve assessed by myocardial contrast echocardiography in rats

Variable Baseline Hyperemia
Controls Diabetics p Controls Diabetics p
Heart rate, min-1 318 ± 27 299 ± 33 NS 315 ± 29 316 ± 25 NS
SBP, mm Hg 131 ± 7 131 ± 13 NS 96 ± 3 100 ± 6 NS
RPP, min-1 mm Hg 41,342 ± 1,234 39,056 ± 1,324 NS 31,339 ± 1,567 31,561 ± 1,234 NS
MBF, ml·min -1·g -1 2.42 ± 0.823 3.75 ± 0.943 NS 5.81 ± 0.99 5.02 ± 0.76 NS
β, min-1 23.3 ± 8.2 27.6 ± 9.1 † 32.3 ± 7.7 37.4 ± 9.9 †
rBV, ml·min -1 0.112 ± 0.045 0.120 ± 0.05 NS 0.191 ± 0.046 0.141 ± 0.043 *
  1. Values are mean ± SD. *p = 0.0001; †p = 0.005.
  2. MBF = myocardial blood flow; rBV = relative blood volume;
  3. RPP = rate-pressure product; SBP = systolic blood pressure.
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