Table 1 The changes in DM patients' parameters.
Parameters | HC | Metformin (months) | Rosiglitazone (months) | |||
|---|---|---|---|---|---|---|
0 | 1 | 2 | 0 | 2 | ||
Fundus | neg | neg | neg | neg | neg | neg |
MAP (mm Hg) | 87.0 ± 2.2 | 99 ± 3.2 | 98.1 ± 1.4 | 99.1 ± 3.6 | 96.1 ± 2.0 | 96.2 ± 0.2 |
Glucose (mg/dL) | 94.0 ± 11.9 | 228.4 ± 15.1b | 135.3 ± 8.3a,b | 135.9 ± 3.2a,b | 235.2 ± 15.8b | 143.1 ± 14.1a,b |
HbA1c (μmol/L) | 5.4 ± 0.2 | 8.9 ± 0.3b | 7.2 ± 0.5a,b | 7 ± 0.1a,b | 10.7 ± 0.6b | 7 ± 0.3a,b |
Calculated GFR | 94.6 ± 2.9 | 99.5 ± 2.1 | 95.7 ± 2.0 | 94.6 ± 2.9 | 95.4 ± 4.8 | 90.1 ± 4.1 |
Cholesterol (mg/dL) | 205.0 ± 1.7 | 203 ± 8.6 | 188.3 ± 9.9 | 188.3 ± 2.2 | 207.3 ± 9.0 | 195.1 ± 4.8 |
Triglycerides (mg/dL) | 120.4 ± 3.2 | 153.2 ± 2.1 | 114.6 ± 26.3 | 129.3 ± 6.5 | 190.2 ± 3.5 | 141.4 ± 5.5 |
HDL (mg/dL) | 58.6 ± 0.7 | 45.9 ± 2.5 | 44.7 ± 3.4 | 43.9 ± 0.9 | 42.04 ± 2.4 | 41.3 ± 0.9 |
LDL (mg/dL) | 114.6 ± 1.3 | 128.4 ± 7.5 | 120.7 ± 8.7 | 118.6 ± 2.1 | 130.0 ± 7.7 | 114.7 ± 2.6 |
Hb (g/dL) | 14.3 ± 0.1 | 14.6 ± 0.4 | 14.0 ± 0.6 | 14.8 ± 0.5 | 14.7 ± 0.3 | 14.4 ± 0.1 |
ALT (U/L) | 20.3 ± 0.5 | 27.3 ± 2.8 | 28.4 ± 5 | 20.3 ± 0.5 | 33.5 ± 6.5 | 24.3 ± 0.7a |
AST (U/L) | 19.6 ± 0.3 | 19.2 ± 1.5 | 24 ± 3.6 | 19.6 ± 0.3 | 23 ± 3 | 17.4 ± 0.3a |
ALP (U/L) | 76.2 ± 6.1 | 87.3 ± 4.8b | 73.7 ± 3.9a | 76.2 ± 6.1a | 83.8 ± 4.5b | 75.3 ± 1.5a |
LDH (U/L) | 283.3 ± 1.9 | 311 ± 17 | 273.2 ± 10.8 | 283.3 ± 1.9 | 270.4 ± 10.8 | 255.8 ± 3.3 |
Insulin (μU/mL) | 7.6 ± 0.8 | 15.2 ± 1.4b | 13.5 ± 1.0b | 11.1 ± 0.9a,b | 17.5 ± 1.8b | 9.5 ± 0.4a,b |