Skip to main content

Table 1 The changes in DM patients' parameters.

From: Intensification of oxidative stress and inflammation in type 2 diabetes despite antihyperglycemic treatment

Parameters HC Metformin (months) Rosiglitazone (months)
   0 1 2 0 2
Fundus neg neg neg neg neg neg
MAP (mm Hg) 87.0 ± 2.2 99 ± 3.2 98.1 ± 1.4 99.1 ± 3.6 96.1 ± 2.0 96.2 ± 0.2
Glucose (mg/dL) 94.0 ± 11.9 228.4 ± 15.1b 135.3 ± 8.3a,b 135.9 ± 3.2a,b 235.2 ± 15.8b 143.1 ± 14.1a,b
HbA1c (μmol/L) 5.4 ± 0.2 8.9 ± 0.3b 7.2 ± 0.5a,b 7 ± 0.1a,b 10.7 ± 0.6b 7 ± 0.3a,b
Calculated GFR 94.6 ± 2.9 99.5 ± 2.1 95.7 ± 2.0 94.6 ± 2.9 95.4 ± 4.8 90.1 ± 4.1
Cholesterol (mg/dL) 205.0 ± 1.7 203 ± 8.6 188.3 ± 9.9 188.3 ± 2.2 207.3 ± 9.0 195.1 ± 4.8
Triglycerides (mg/dL) 120.4 ± 3.2 153.2 ± 2.1 114.6 ± 26.3 129.3 ± 6.5 190.2 ± 3.5 141.4 ± 5.5
HDL (mg/dL) 58.6 ± 0.7 45.9 ± 2.5 44.7 ± 3.4 43.9 ± 0.9 42.04 ± 2.4 41.3 ± 0.9
LDL (mg/dL) 114.6 ± 1.3 128.4 ± 7.5 120.7 ± 8.7 118.6 ± 2.1 130.0 ± 7.7 114.7 ± 2.6
Hb (g/dL) 14.3 ± 0.1 14.6 ± 0.4 14.0 ± 0.6 14.8 ± 0.5 14.7 ± 0.3 14.4 ± 0.1
ALT (U/L) 20.3 ± 0.5 27.3 ± 2.8 28.4 ± 5 20.3 ± 0.5 33.5 ± 6.5 24.3 ± 0.7a
AST (U/L) 19.6 ± 0.3 19.2 ± 1.5 24 ± 3.6 19.6 ± 0.3 23 ± 3 17.4 ± 0.3a
ALP (U/L) 76.2 ± 6.1 87.3 ± 4.8b 73.7 ± 3.9a 76.2 ± 6.1a 83.8 ± 4.5b 75.3 ± 1.5a
LDH (U/L) 283.3 ± 1.9 311 ± 17 273.2 ± 10.8 283.3 ± 1.9 270.4 ± 10.8 255.8 ± 3.3
Insulin (μU/mL) 7.6 ± 0.8 15.2 ± 1.4b 13.5 ± 1.0b 11.1 ± 0.9a,b 17.5 ± 1.8b 9.5 ± 0.4a,b
  1. a P < 0.05, treated DM patients vs. untreated DM patients;
  2. b P < 0.05, untreated DM patients vs. HC subjects