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Table 1 General characteristics of DGKζ-TG and WT mice at 8 weeks after STZ injection.

From: Diacylglycerol kinase ζ inhibits myocardial atrophy and restores cardiac dysfunction in streptozotocin-induced diabetes mellitus

 

WT control

DGKζ-TG control

WT STZ

DGKζ-TG STZ

BW, g

32.08 ± 0.70

32.3 ± 0.65

22.37 ± 0.91*

22.8 ± 0.54§

BG, mg/dl

155.4 ± 0.47

157.7 ± 0.54

465.8 ± 0.61*

455.3 ± 0.53§

HW, mg

147 ± 0.02

142 ± 0.01

92 ± 0.02*

110 ± 0.02§ddag

LVW, mg

107 ± 0.01

105 ± 0.01

69 ± 0.01*

77 ± 0.01§

HW/BW ratio, mg/g

4.58 ± 0.13

4.41 ± 0.08

4.00 ± 0.14*

4.44 ± 0.12‡

LVW/BW ratio, mg/g

3.32 ± 0.07

3.24 ± 0.05

3.0 ± 0.09*

3.25 ± 0.08‡

  1. Data are mean ± SEM from 15 mice for each group. BW, body weight; BG, blood glucose; HW, heart weight; LVW, left ventricular weight. *P < 0.01 vs. WT control, ‡P < 0.05 vs. WT STZ, §P < 0.01 vs. DGKζ-TG control.
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Cardiovascular Diabetology

ISSN: 1475-2840