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Table 3 Chromosomal location, tissue distribution and transcript information of genes encoding glucose transporters

From: Important genetic checkpoints for insulin resistance in salt-sensitive (S) Dahl rats

Gene Symbol Gene name Chromosomal Location Tissue Distribution Function Transcript Information
Slc2a1 facilitated glucose transporter member 1 (Glucose transporter type 1) (GLUT-1) chr5:139690804–139719021 All tissues (abundant in brain and erythrocytes) Basal uptake Exons: 10
Transcript length: 2,365 bps
Protein length: 492 residues
Slc2a2 solute carrier family 2, facilitated glucose transporter member 2 (Glucose transporter type 2) (GLUT-2) chr2:116036427–116065870 Liver, pancreatic islet cells, retina Glucose sensing Exons: 12
Transcript length: 2,578 bps
Protein length: 524 residues
Slc2a3 solute carrier family 2, facilitated glucose transporter member 3 (Glucose transporter type 3) (GLUT-3) chr4:159210019–159221248 All tissues specially the brain Supplements GLUT1 in tissues with high energy demand Exons: 9
Transcript length: 1,467 bps
Protein length: 488 residues
Slc2a4 solute carrier family 2, facilitated glucose transporter member 4 (Glucose transporter type 4) (GLUT-4). chr10:56,786,705–56,792,209. Muscle, fat, heart Insulin responsive Exons: 11
Transcript length: 2,506 bps
Protein length: 509 residues
Slc2a8 solute carrier family 2, facilitated glucose transporter member 8 (Glucose transporter type 8) (GLUT-8) chr3:11962578–11972099 hippocampal neurons, testis, whole brain   Exons: 10
Transcript length: 2,087 bps
Protein length: 478 residues
Naglt1 Sodium dependant glucose transporter 1 chr20:44,147,331–44,176,308. In all cells   Exons: 4
Transcript length: 1,455 bps
Protein length: 484 residues
Slc37a4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 chr 8: 47,363,896–47,369,981. Liver, Adipocytes   Exons: 9
Transcript length: 2,080 bps
Protein length: 429 residues