Figure 1From: Important genetic checkpoints for insulin resistance in salt-sensitive (S) Dahl ratsMechanism of High Salt-Induced Insulin Resistance in Dahl S rats. Our proposed model of high salt-induced insulin resistance in Dahl S rats depends on the combined contributions of high salt and genetic defects along the insulin signaling and inflammatory pathways, which in turn predispose Dahl S rats to an augmented inflammatory response and overt insulin resistance.Back to article page