On the use of a continuous metabolic syndrome score in pediatric research

Table 1 Summary of approaches used to calculate the continuous metabolic syndrome score in pediatric epidemiological research.

Study	Obesity	Lipids	Glucose or Insulin	Blood Pressure	Other	Statistical approach
Bogolusa Heart Study [21]	-	TC:HDL	Insulin	SBP		Sum of the individual rankings by age-, sex-, and race-specific levels
Young Danes [28]	Skinfolds	TC, HDL-C, TG	-	SBP and DBP	smoking	Upper centiles
Cardiovascular Risk in Young Finns [22]	-	TC and HDL-C	-	DBP		Upper tertile
European Youth Heart Study [20]	Skinfolds	HDL-C and TG	Glucose and insulin	Average of SBP and DBP		Sum of six Z scores divided by 6
European Youth Heart Study [19]	Skinfolds	TG and TC:HDL-C	HOMA	SBP	Aerobic fitness	Sum of Z scores
Corpus Christi Child Heart Study [23]	BMI	HDL-C and TG	Insulin	SBP		2 approaches: 1) sum of Z scores, and 2) principal components analysis
Quebec Family Study [24]	Skinfolds	HDL-C, TG, and TC:HDL-C	Glucose	MAP		principal component analysis
Aerobic Center Longitudinal Study [27]	WC	HDL-C and TG	Glucose	MAP		Sum of age-standardized residuals
Australian Health and Fitness Study [34]	WC	HDL-C and TG	-	MAP		Sum of age-standardized residuals
Physical Activity across the Curriculum [38]	WC	HDL-C and TG	HOMA	MAP		Sum of age-, sex-, and race-standardized residuals

BMI, body mass index; WC, waist circumference; TC, total cholesterol; HDL-C, high density lipoprotein-cholesterol; TG, triglycerides; HOMA, homeostasis model assessment; SBP, systolic blood pressure; DBP, diastolic blood pressure; MAP, mean arterial pressure.

ISSN: 1475-2840