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Table 1 Clinical and biochemical parameters for 167 subjects with type 2 diabetes, stratified according to cardiac function

From: Association between intrarenal arterial resistance and diastolic dysfunction in type 2 diabetes

 

Total cohort (n = 167)

Normal cardiac function (n = 59)

Diastolic dysfunction alone (n = 66)

Diastolic and systolic dysfunction (n = 30)

Intrarenal RI

0.69 ± 0.01

0.66 ± 0.06

0.72 ± 0.06**

0.71 ± 0.06**

Age (years)

62 ± 12

55 ± 13

66 ± 9*

66 ± 12*

Sex (% male)

59%

59%

54%

72%

Diabetes duration (years)

11 ± 8

9 ± 6

13 ± 8*

10 ± 7

Obese BMI (>30 kg/m2, %)

57%

48%

60%

56%

History of CVD (%)

36%

23%

32%

69%*

HbA1c (%)

7.7 ± 1.5

8.1 ± 1.5

7.6 ± 1.3*

7.4 ± 1.9*

Metformin use(%)

68%

80%

55%*

69%

Sulphonylurea use (%)

57%

62%

50%

72%

Glitazone use (%)

19%

31%

11%*

17%

Insulin use (%)

42%

45%

46%

24%

Hypertension (%)

81%

69%

85%*

90%*

Systolic BP (mmHg)

140 ± 17

135 ± 17

144 ± 18

141 ± 15

Diastolic BP (mmHg)

75 ± 8

76 ± 8

74 ± 8

76 ± 9

RAS inhibitor use (%)

72%

54%

84%*

83%*

Number of antihypertensives (n)

1.9 ± 1.4

1.3 ± 1.3

2.1 ± 1.4*

2.7 ± 1.5*

Total cholesterol (mM)

4.7 ± 0.9

4.9 ± 1.0

4.8 ± 0.8

4.6 ± 1.0

Triglycerides (mM)

2.1 ± 1.2

2.3 ± 1.3

2.0 ± 1.1

2.3 ± 1.4

Treatment for dyslipidaemia

63%

58%

53%

90%*

History of retinopathy

27%

14%

44%*

17%

iGFR (ml/min/1.73 m2)

93 ± 32

111 ± 27

82 ± 27*

73 ± 30*

GFR< 60 (ml/min/1.73 m2)

22%

6%

25%*

39%*

AER > 20 (μg/min)

45%

41%

39%

59%*

  1. Data for continuous variables are mean ± SD. Data for categorical variables are expressed as proportions.
  2. * p < 0.05, ** p < 0.01 vs individuals with normal cardiac function on TTE,