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Table 3 Comparison of MRI-derived LV volume and systolic function between control and diabetic mice.

From: Early myocardial dysfunction in streptozotocin-induced diabetic mice: a study using in vivo magnetic resonance imaging (MRI)

 

Control (n = 8)

Diabetic (n = 12)

P value

Heart Rate (bpm)

470 ± 11

446 ± 11

NS

End-diastolic volume (μl)

46.0 ± 1.1

44.8 ± 1.0

NS

End-systolic volume (μl)

18.3 ± 0.5

22.6 ± 0.5

< 0.001

Stroke volume (μl)

27.8 ± 0.7

22.3 ± 0.8

< 0.001

Ejection fraction (%)

60.3 ± 0.6

49.6 ± 1.3

< 0.001

Cardiac output (ml/min)

13.1 ± 0.4

9.9 ± 0.5

< 0.05

Fractional shortening (%)

37.7 ± 1.4

24.2 ± 1.6

< 0.001

  1. Values are mean ± SEM.
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Cardiovascular Diabetology

ISSN: 1475-2840