Blood glucose levels in control and diabetic mice. Mice were treated with streptozotocin (STZ) or citrate buffer on days 0 and 1. The onset of hyperglycemia occurred within one week after STZ injection. Mice were given low dosages of long acting insulin to maintain blood glucose at 19–25 mmol/l. Values are mean ± SEM. Control, n = 12; diabetic, n = 8.